azido-peg-8-acid

Azido-PEG8-acid is a non-cleavable 8-unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.

2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

N-(Azido-PEG3)-N-(PEG2-amine)-PEG3-acid is a polyethylene glycol (PEG)-based linker frequently used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Azido-PEG36-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG2-C2-sulfonic acid is a polyethylene glycol (PEG) derived linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Azido-PEG3-Sulfone-PEG4-acid, a polyethylene glycol (PEG) derivative, is frequently employed as a linker in the construction of proteolysis targeting chimeras (PROTACs) [1].

Azido-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as the conjugate CPT-APO (CPT: Camptothecin.

N-(Azido-PEG2)-N-Boc-PEG3-acid is a polyethylene glycol (PEG)-derived linker compound specifically designed for PROTAC synthesis [1].

Azido-PEG9-acid, a non-cleavable 9-unit PEG ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).

Azido-PEG1-C2-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system [within cells].

N-(Azido-PEG3)-N-bis(PEG4-acid) is a polyethylene glycol-based linker, designed for the synthesis of PROTACs [1].

Azido-PEG3-phosphonic acid ethyl ester, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].

Azido-PEG3-aminoacetic acid-NHS ester is a PEGylation-based linker for the synthesis of PROTACs[1], providing a versatile and efficient approach.

Azido-PEG10-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG2)-N-Boc-PEG4-acid is a polyethylene glycol (PEG)-based linker developed for synthesizing PROteolysis TArgeting Chimeras (PROTACs)[1].

N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

N-(Azido-PEG3)-N-Boc-PEG3-acid is a polyethylene glycol (PEG)-based linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Azido-PEG12-acid (PROTAC Linker 13) is a polyethylene glycol-based linker utilized in the synthesis of PROTACs.

N-(Azido-PEG3)-N-bis(PEG3-acid) is a polyethylene glycol (PEG)-based linker that incorporates an azido group and two PEG3-acid moieties, widely applicable in the synthesis of proteolysis targeting chimeras (PROTACs) for the selective degradation of target proteins[1].

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEGylated PROTAC linker with azide, fluorescein, and carboxylic acid functional groups.

Azido-PEG16-acid is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a polyethylene glycol (PEG)-derived PROTAC linker designed for PROTAC synthesis[1].

Azido-PEG6-acid is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras] that connects two essential ligands, crucial for the formation of PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Azido-PEG24-acid is a PEG-based linker for PROTACs, crucial for joining two essential ligands and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a polyethylene glycol (PEG)-based linker used in the development of proteolysis targeting chimeras (PROTACs)[1].

Azido-PEG11-acid is a PEG-based linker for PROTACs [proteolysis-targeting chimeras], facilitating the connection of two essential ligands necessary for PROTAC molecule formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Azido-PEG2-C2-acid is a PEG-based linker for PROTACs that joins two essential ligands, facilitating PROTAC molecule formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-NH-PEG3-acid is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group, primarily used in PROTAC synthesis [1].

Azido-C2-SS-PEG2-C2-acid is a cleavable PEG linker with two units used in the synthesis of antibody-drug conjugates (ADCs) [1].

N-(Azido-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker, facilitating PROTAC synthesis [1].

Azido-PEG4-C2-acid, a PEG-based PROTAC linker, is utilized in the synthesis of vRucaparib-TP4. It serves as a non-cleavable 4 unit PEG ADC linker for antibody-drug conjugate (ADC) synthesis.