azm 112

Renzapride is a 5-HT3 antagonist and 5-HT4 agonist. Renzapride also functions as a 5-HT2B antagonist and has some affinity for the 5-HT2A and 5-HT2C receptors.

(S)-Renzapride ((S)-BRL 24924), an isomer of Renzapride, acts as a 5-HT4 receptor agonist with a K_i of 115 nM and antagonizes 5HT2b and 5HT3 receptors. It is utilized in studies focused on constipation-predominant irritable bowel syndrome (C-IBS).

Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist.Renzapride can be used in the study of constipation-predominant irritable bowel syndrome (C-IBS).