bay-598 r-isomer

BAY-598 R-isomer is the R-isomer of BAY589, which is used as a reference compound. It is is an inhibitor of lysine N-methyltransferase (SMYD2) and is selective for SMYD2 over protease-activated receptor 1 (PAR1).

BAY-R 1005, a synthetic glycolipid analogue (GLA) with immunoenhancing properties, is designed to modulate antibody synthesis [1].

MKC-963 is a platelet aggregation inhibitor and autoinducer of CYP3A4.

(R)-BAY-899 is an R-isomer of BAY-899. BAY-899 is a selective, orally active luteinizing hormone receptor (LH-R) antagonist that acts on hLH (human LH) (IC50: 185 nM) and rLH (rat LH) (IC50: 46 nM).

Midodrine is a vasopressor/antihypertensive agent for the treatment of symptomatic postural hypotension.

(R)-(+)-Bay-K-8644 is a Ca2+ channel inhibitor that inhibits Ba2+ currents (IBa), induces central respiratory depression in cats, and inhibits platelet activation through competitive antagonism of thromboxane A2-prostaglandin H2 receptors.

BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.

INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.

(R,R)-BAY-Y 3118, the R-enantiomer of BAY-Y 3118, exhibits weak bactericidal activity.

BAY-598 is a selective inhibitor of SMYD2 with IC50 values of 27 nM.

Oxybutynin R-isomer , also known as Aroxybutynin, is a muscarinic receptor antagonist. Aroxybutynin is the optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Oxybutynin exerts direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. It exhibits one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. No blocking effects occur at skeletal neuromuscular junctions or autonomic ganglia (antinicotinic effects).

(R)-BAY-85-8501 is the less active enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent Human Neutrophil Elastase (HNE)inhibitor(IC50 of 65 pM).

Bay 65-1942 R form is the less active R-form of Bay 65-1942. Bay 65-1942 is a selective and ATP-competitive IKKβ inhibitor.