bcn ​exo ​peg3 ​nh2

BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker used in PROTAC synthesis[1].

NH2-C2-NH-Boc (PROTAC Linker 22), an alkyl chain-based PROTAC linker, can be used in the synthesis of PROTACs.

NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

NH2-C4-NH-Boc (compound 15) is a PROTAC linker of the Alkyl ether class, suitable for synthesizing various PROTAC molecules.

Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and a linker[1].

Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate.

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative featuring a hydroxyl group and a Boc-protected amino group, used as a PROTAC linker.

Boc-NH-C12-NH2 is an alkyl ether-based PROTAC linker suitable for use in PROTAC synthesis.

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate that integrates the (S,R,S)-AHPC-based VHL ligand with a 3-unit PEG linker.

Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras).

Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a 3-unit PEG linker, used in PROTAC technology.

Boc-NH-PEG3-CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis [1].

Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.

Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.

Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

Thalidomide-O-amido-C3-PEG3-C1-NH2 is a synthesized conjugate compound serving as an E3 ligase ligand-linker, featuring a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for use in PROTAC technology.

NH2-PEG3 hydrochloride is a PEG-based linker for PROTACs, crucial for joining two essential ligands to form PROTAC molecules. This compound facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 is a synthetic E3 ligase ligand-linker conjugate composed of a VHL ligand and a linker, utilized in PROTAC BRD4 Degrader-5 and PROTAC BRD4 Degrader-5-CO-PEG3-N3.

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a polyethylene glycol (PEG)-based linker designed for constructing PROTACs.

m-PEG2-O-Ph-3-NH2 is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Fmoc-NH-PEG5-C2-NH2 is a PEG-based linker for PROTACs that joins two essential ligands, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-NH-PEG3-acid is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable triethylene glycol linker featuring propargyl and N-hydroxysuccinimide (NHS) functional groups, used in the synthesis of antibody-drug conjugates (ADCs)[1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

BCN-PEG3-oxyamine is a non-cleavable, three-unit polyethylene glycol linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Thalidomide-NH-C10-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates CRBN protein recruitment and, when conjugated with a linker, forms PROTACs [1].

Thalidomide-5-NH-PEG1-NH2 hydrochloride is a Thalidomide-based cereblon ligand designed for CRBN protein recruitment. It facilitates the formation of PROTAC molecules by linking to target protein ligands, such as THAL-SNS-032, via a connector.

NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a 28-unit polyethylene glycol (PEG) linker with a cleavable bond, frequently used in the production of antibody-drug conjugates (ADCs)[1].

BCN-PEG3-VC-PFP ester, a three-unit PEG ADC linker, is cleavable and commonly used in the synthesis of antibody-drug conjugates (ADCs) [1].

m-PEG-NH2 (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH-bis(PEG3-C2-NH-Boc) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Boc-NH-PEG3-sulfonic acid, a polyethylene glycol (PEG) derived linker, is utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology.

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

NH-bis(PEG3-acid) is a PEG-based linker utilized in PROTACs, connecting two essential ligands crucial for creating PROTAC molecules. This linker leverages the ubiquitin-proteasome system within cells to enable selective protein degradation.

Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker and a cleavable 2-unit PEG ADC linker, used in the synthesis of PROTACs [1] and antibody-drug conjugates (ADCs) [2], respectively.

endo-BCN-PEG3-mal is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Boc-NH-PEG15-NH2 is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Thalidomide-NH-C9-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein. This compound can be conjugated to a protein-targeting ligand via a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs) [1].

Cbz-NH-PEG3-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands crucial for PROTAC molecule formation. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.