bcn-exo-peg3-nh2

BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker used in PROTAC synthesis[1].

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

endo-BCN-PEG3-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands integral to PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor used as a toxin payload in antibody-drug conjugates, is conjugated via a DBCO-(PEG)3-vc-PAB linker.

Thalidomide-NH-CBP p300 ligand 2 (P-007) is a PROTAC-based compound engineered to degrade the proteins CBP and p300, functioning as a molecular antagonist (WO2020173440).

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Exo-BCN-PEG2-Boc-amine is a PEG derivative containing a BCN group and a Boc-protected amine. PEG Linkers and PEG derivatives may be useful in the development of antibody-drug conjugates.

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

exo BCN-O-PNB is a alkyl ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG-amine (MW 3400) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-derived PROTAC linker used for synthesizing PROTACs [1].

Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker used for the synthesis of PROTACs [1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker, incorporating a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for PROTAC technology applications.

Boc-NH-PEG-amine (MW 2000) is a polyethylene glycol (PEG) linker utilized in PROTAC synthesis[1].