benzenesulfonamide

Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.

4-((benzo[g]quinolin-4-ylamino)methyl)benzenesulfonamide is a chemical agent.

Benzenesulfonamide, N-(4-chloro-3-(trifluoromethyl)phenyl)-4-fluoro- is a bioactive chemical.

4-Chloro-N-(2,5-dimethylphenyl)benzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T64554 and the CAS number is 7454-68-4.

4-Methyl-N,N-bis(2-(4-methylphenylsulfonamido)ethyl)benzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T65706 and the CAS number is 56187-04-3.

4-Amino-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide monosodium salt is a useful organic compound for research related to life sciences and the catalog number is T64735.

Benzenesulfonamide, 3-((ethylphenylamino)methyl)-N,N-dimethyl- is a bioactive chemical.

Benzenesulfonamide, N-(2-chloro-5-(trifluoromethyl)phenyl)-4-fluoro- is a bioactive chemical.

4-(2-(1-(p-Tolyl)ethylidene)hydrazinyl)benzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T64550 and the CAS number is 1061214-06-9.

4-amino-N-(4-nitrophenyl)benzenesulfonamide-d4 is a deuterated compound of 4-amino-N-(4-nitrophenyl)benzenesulfonamide.

Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension.

4-((benzo[g]quinolin-4-yl(methyl)amino)methyl)-N,N-dimethylbenzenesulfonamide is a chemical agent.

ENT 25641 is a bio-active chemical. Detailed information has not been published.

BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protein D (RagD) with IC50 of 46.11 nM. BC-LI-0186 competitively binds the RagD interaction site of LRS with Kd of 42.1 nM and has no effect on LRS-vps34, LRS-eprs, RagB-RagD association, mTORC1 complex formation. BC-LI-0186 potently inhibits the activity of tumor-associated MTOR mutants and the growth of rapamycin-resistant cancer cells. BC-LI-0186 can be used for lung cancer-related research.

Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.

Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.

4-Acetamidobenzenesulfonamide used in proteomics research and is an anti-infective agent

4-Hydrazinylbenzenesulfonamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65814 and the CAS number is 17852-52-7.

4-Amino-N-phenylbenzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T67361 and the CAS number is 127-77-5.

Phosphorothioic acid, O,O-dimethyl ester, O-ester with m-hydroxy-N,N- dimethylbenzenesulfonamide is a bioactive chemical.

5-Formyl-2-methoxybenzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T67147 and the CAS number is 105764-07-6.

4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T65997 and the CAS number is 169280-56-2.

Phosphorothioic acid, O,O-diethyl ester, O-ester with m-hydroxy-N,N-dimethylbenzenesulfonamide is a bioactive chemical.

13(S)HODE Ethanolamide is a biochemical used to inhibit the adhesion of tumor cells

Apricoxib, also known as Benzenesulfonamide 42(4ethoxyphenyl)4methyl1Hpyrrol1yl, is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis.

COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 = 10.4 μM), as well as 5-lipoxygenase (5-LOX; IC50 = 2.4 μM). Additionally, it inhibits the transmembrane isoforms of human carbonic anhydrase IX and XII with nanomolar class Ki values. Demonstrating analgesic and anti-inflammatory properties, COX-2-IN-30 is devoid of acute gastric effects, avoiding ulcerogenic activity [1].

HMN-154 is a novel benzenesulfonamide anticancer compound. It is able to interact with NF-YB and interrupt the binding of NF-Y heterotrimer to DNA.

Suclofenide is a benzenesulfonamide derivative that acts as an anticonvulsant and antiepileptic agent. In preclinical models, it showed potent anticonvulsant activity against electroshock and pentylenetetrazole-induced convulsions in mice. Sublethal toxicity was demonstrated by lethargy, myoclonic jerks and diarrhea.

Chlorthalidone-d4 is a deuterated compound of Chlorthalidone. Chlorthalidone has a CAS number of 77-36-1. Chlorthalidone is a benzenesulfonamide-phthalimidine that tautomerizes to a BENZOPHENONES form. It is considered a thiazide-like diuretic.