benzyl-peg-1-tos

Compound Fr12729 is a useful organic compound for research related to life sciences. The catalog number is Fr12729 and the CAS number is 4727-72-4.

1-Benzyl-3-Phenylthiourea (1-Benzyl-3-Phenyl-2-Thiourea) can be used as a sensing material for the detection of nerve agents and related stimulants.

N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide inhibiting the entry of Ebola virus in host cells by binding to the surface glycoprotein, the compound inhibited the Ebola virus with EC50 of 3.9 μM.

1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).

Benzyl-PEG1-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine   acetic acid benzyl ester is a useful organic compound for research related to life sciences and the catalog number is TNU1477.

1-Benzyl-4-(phenylamino)piperidine-4-carbonitrile is a useful organic compound for research related to life sciences. The catalog number is T67109 and the CAS number is 968-86-5.

Di(adamantan-1-yl)(benzyl)phosphine is a useful organic compound for research related to life sciences and the catalog number is T65005.

2-(Benzyl(methyl)amino)-1-(3-hydroxyphenyl)ethanone hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65560 and the CAS number is 71786-67-9.

(S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66621 and the CAS number is 105590-97-4.

1-(b-D-Xylofuranosyl)-N6-(m-trifluoromethyl benzyl) adenine is a Nucleoside Derivative - Xylo-nucleoside, 6-Modified purine nucleoside, Fluoro-modified nucleoside.

N4-Boc-5-fluorocytosin-1-yl-acetic acid benzyl ester; is a PNA-related Derivative.

Benzyl [5-O-benzoyl-β-D-apiofuranosyl(1→2)]-β-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN5741 and the CAS number is 1097040-08-8.

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-N-methyl-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T67192 and the CAS number is 923036-30-0.

cis-1-Benzyl-4-(methoxycarbonyl)pyrrolidine-3-carboxylic acid is a Other heterocyclic compound - pyrrolidine, building block - electrophile.

(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65526 and the CAS number is 1354486-07-9.

(S)-1-Benzyl 2-tert-butyl pyrrolidine-1,2-dicarboxylate is a useful organic compound for research related to life sciences. The catalog number is T65611 and the CAS number is 16881-39-3.

18:1 PEG-PE, a polyethylene glycol/phosphatidylethanolamine conjugate, serves as a vehicle for drug delivery [1].

5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine nucleoside analog, exhibits broad antitumor activity primarily against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, among others [1].

5-Methylcytosin-1-yl-acetic acid benzyl ester is a PNA-related Derivative.

(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67699 and the CAS number is 2365497-12-5.

(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66079 and the CAS number is 1062580-52-2.

1-(4-(2-(Azepan-1-yl)ethoxy)benzyl)-5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-1H-indole is a useful organic compound for research related to life sciences. The catalog number is T66992 and the CAS number is 198480-21-6.

(S)-1-Benzyl 2-methyl pyrrolidine-1,2-dicarboxylate is a useful organic compound for research related to life sciences. The catalog number is T65353 and the CAS number is 5211-23-4.

Other heterocyclic compound - pyrrolidine, building block - electrophile and nucleophile

1-Benzyl-I3C is an NEDD4-1 inhibitor.

m-PEG-Tos (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Benzyl-PEG2-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

1-(2-Fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione is a useful organic compound for research related to life sciences. The catalog number is T66467 and the CAS number is 830346-47-9.

5-Fluorocytosin-1-yl-acetic acid benzyl ester is a PNA-related Derivative.

Wnt signaling is required for direct multiple biological processes and also plays key roles in the pathogenesis of various diseases. Cyclic AMP response element-binding protein (CREB) is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Via generating a transcriptionally active complex with β-catenin, CREB acts as a mediator of Wnt signaling.ICG-001 is an inhibitor of β-catenin/CREB mediated transcription. The direct cellular target of ICG-001 is CREB. the inhibitory IC50of ICG-001 against β-catenin/CREB mediated transcription was 3 μM. ICG-001 treatment at the concentration of 25 μM for 24h significantly increased caspase activity in both colon cancer cell lines SW480 and HCT116 cell lines but not in normal colonic epithelial cells CCD-841Co. In a cell growth inhibition assay, the IC50s of ICG-001 against SW480 and HCT116 cells were 4.43 μM and 5.95 μM, respectively.In a SW620 nude mouse xenograft model, an water-soluble analog of ICG-001 given at the dose of 150 mg/kg i.v. once in every 2 days dramatically suppressed tumor growth. In a bleomycin-induced pulmonary fibrosis mice model, ICG-001 given at the dose of 5 mg/kg per day reversed pulmonary fibrosis. In a rat myocardial infarction model, ICG-001 was administrated subcutaneously at the dose of 50 mg/kg/day for 10 days which significantly improved cardiac contractile function after myocardial infarction in the rats.

(S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate is a useful organic compound for research related to life sciences. The catalog number is T66075 and the CAS number is 16217-15-5.

1-Benzyl-4-(phenylamino)piperidine-4-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67643 and the CAS number is 85098-64-2.

1-Benzyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate is a useful organic compound for research related to life sciences. The catalog number is T65605 and the CAS number is 155075-23-3.

1-Benzyl-4-methyl-3-(methylamino)piperidine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66156 and the CAS number is 1228879-37-5.