biotin peg2 c4 alkyne

Biotin-PEG2-C4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

PC Biotin-PEG3-alkyne is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).

2-(2,6-dioxopiperidin-3-yl)-4-((7-hydrox is protac.

(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

Dde Biotin-PEG4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly employed as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

DBCO-(PEG2-VC-PAB-MMAE)2 consists of Monomethyl auristatin E (MMAE), a toxin payload in antibody-drug conjugate [1], conjugated to the cleavable linker DBCO-(PEG2-VC-PAB)2. MMAE, a potent tubulin inhibitor, serves as the cytotoxic component in this formulation.

Biotin-PEG2-OH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Biotin-PEG4-amide-Alkyne is a polyethylene glycol (PEG)-based linker, primarily used for synthesizing PROTACs[1].

Biotin-PEG2-C1-aldehyde is a polyethylene glycol (PEG)-based linker utilized in synthesizing proteolysis targeting chimeras (PROTACs) [1].

TAMRA-Azide-PEG-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Biotin alkyne is a useful organic compound for research related to life sciences and the catalog number is T66674.

Biotin-PEG2-C2-iodoacetamide (Biotin-PEG2-iodoacetamide) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

CHO-C-PEG2-C-CHO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1].

Diazo Biotin-PEG3-alkyne is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

2-(Azido-PEG2-amido)-13-propandiol is a Polyethylene glycol (PEG)-based PROTAC linker used for the synthesis of PROTACs[1].

Biotin-PEG2-C6-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

Biotin-PEG2-CH2CH2N3 is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

m-PEG2-4-nitrophenyl carbonate is a PEG-derived linker for PROTACs synthesis[1].

Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Dde Biotin-PEG4-TAMRA-PEG4 Alkyne, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].

Biotin-PEG2-NH-Boc is a PEG-based PROTAC linker labelled with biotin, which enables its application in PROTAC synthesis[1].

Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Lenalidomide 4'-PEG2-azide, a Lenalidomide-derived Cereblon ligand, facilitates the recruitment of CRBN protein. This compound can be tethered via a linker to a protein ligand, enabling the formation of PROTAC [1].

Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

N-(m-PEG4)-N'-(Biotin-PEG2-amido-PEG4)-Cy5 is a polyethylene glycol (PEG) derived linker commonly utilized in PROTAC synthesis[1].

Biotin-PEG2-aldehyde is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Biotin-PEG-triethoxysilane (MW 2000) is a polyethylene glycol (PEG) derivative functionalized with triethoxysilane and biotin moieties. This compound serves as a PEG-based linker for PROTAC synthesis, facilitating the targeted degradation of proteins of interest.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate compound that combines a Thalidomide-based cereblon ligand and a linker, which is commonly utilized in PROTAC technology. This compound acts as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Biotin-PEG4-PC-PEG4-alkyne is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker utilized in the synthesis of PROTACs[1].

UV Cleavable Biotin-PEG2-Azide, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker. This specific linker is utilized in the synthesis of PROTACs, or proteolysis targeting chimeras [1].

DSPE-PEG-Biotin (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker utilized in the synthesis of PROTACs[1].

Biotin-PEG-triethoxysilane (MW 5000) is a PEG-based PROTAC linker utilized for PROTAC synthesis[1].

(2-Pyridyldithio)-PEG2-Boc is a polyethylene glycol-based PROTAC linker utilized for the synthesis of PROTACs[1].

DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1]. DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1]. [1]. Mengzhu Zheng, et al. Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP. J Med Chem. 2021 May 26.

DBCO-NHCO-PEG2-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG2-NHS ester is a biotinylated, polyethylene glycol (PEG)-based linker, which is utilized in PROTAC synthesis for the purpose of biotin attachment[1].

Biotin-PEG2-Mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(+)-Biotin-PEG2-hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based compound utilized for the synthesis of PROTACs. This chemical compound serves as a linker in the development of PROTACs[1].

Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker used in PROTAC synthesis.

Biotin-PEG-amine (MW 3400) is a polyethylene glycol (PEG)-based linker compound utilized for PROTAC synthesis [1].

Biotin-PEG-Biotin (MW 1000) is a PEG-derived PROTAC linker employed in PROTAC synthesis[1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized conjugate compound known as an E3 ligase ligand-linker. It incorporates a cereblon ligand based on Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology applications.