biotin peg4 nhs ester

Biotin-PEG4-NHS ester, a biotinylated and PEGylated N-hydroxysuccinimide ester, serves as a linker in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).

N3-C4-NHS ester, a non-cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).

Azido-PEG12-NHS ester, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

N3-Ph-NHS ester is a noncleavable ADC linker that can be utilized in the synthesis of antibody-drug conjugates (ADCs).

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker employed in PROTAC synthesis [1].

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester]

Fmoc-PEG12-NHS ester, a PEG-based linker for PROTACs, facilitates the joining of two essential ligands, crucial for the formation of PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

Tetrazine-Ph-NHCO-C3-NHS ester is a PEG-derived linker used for PROTAC synthesis.

Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) is a nonclaevable linker used for antibody-drug-conjugation (ADC).

Ald-Ph-NHS ester is a non-cleavable linker utilized in antibody-drug conjugation (ADC).

Boc-NH-O-C1-NHS ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Dde Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition, crucial in synthesizing various PROTACs, including BI-3663, a selective PTK2 FAK PROTAC. Using cereblon ligands, it targets E3 ligases to degrade PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].

Methyltetrazine-PEG13-NHS ester, a polyethylene glycol (PEG)-derived linker, is designed specifically for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based linker derived from fluorenylmethoxycarbonyl (Fmoc) used for the efficient synthesis of PROTACs (proteolysis-targeting chimeras)[1], offering a practical solution for connecting desired molecules and targeting specific proteins for degradation.

m-PEG37-NHS ester is a PEG-based linker for PROTACs, which connects two essential ligands crucial for PROTAC molecule formation. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

DBCO-NHS ester is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).

Mal-amido-PEG1-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that incorporates a maleimide functional group and an N-hydroxysuccinimide (NHS) ester. The NHS ester offers a means to specifically modify primary amines (-NH2) present in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

Tetrazine-Ph-NHS ester is an alkyl ether-based PROTAC linker commonly used for synthesizing PROTACs[1].

m-PEG4-phosphonic acid ethyl ester is a PEGylation-based linker used in the design and synthesis of PROTACs, which are heterobifunctional molecules that facilitate targeted protein degradation[1].

Bromoacetamido-PEG4-NHS ester is a PEGylated N-hydroxysuccinimide ester linker designed for PROTAC synthesis, facilitating the creation of protein-targeted chimeras (PROTACs)[1].

Bromo-PEG2-NHS ester, a PEG-based linker for PROTACs, connects two essential ligands necessary for PROTAC molecule formation and enables selective protein degradation through the ubiquitin-proteasome system within cells.

Mal-amido-PEG4-TFP ester, a PEG-based PROTAC linker, finds utility in the synthesis of PROTACs[1].

Azido-PEG8-C1-NHS ester is a polyethylene glycol (PEG)-based linker designed for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Biotin-bis-amido-SS-NHS is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs.

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].

Fluorescein-PEG6-bis-NHS ester, a polyethylene glycol (PEG)-based linker, is utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Biotin-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands for forming PROTAC molecules and enables selective protein degradation via the ubiquitin-proteasome system within cells.

Azido-PEG4-4-nitrophenyl carbonate, a PEG-derived PROTAC linker, enables the synthesis of PROTACs[1].

Propargyl-O-C1-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

Boc-N-PEG5-C2-NHS ester is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation by harnessing the ubiquitin-proteasome system within cells.

Azido-PEG3-S-PEG4-t-butyl ester, a PEG-based PROTAC linker, is used in PROTAC synthesis [1].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized in synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Iodoacetyl-PEG4-NHS ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG36-NHS ester is a PEG-based linker used in PROTAC development, joining two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG6-NHS ester is a cleavable 6-unit polyethylene glycol (PEG) linker, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1], and serves as a PEG- and alkyl ether-based linker for the synthesis of proteolysis targeting chimeras (PROTACs)[2].

N3-PEG4-C2-Pfp ester is a noncleavable, four-unit polyethylene glycol linker used in the fabrication of antibody-drug conjugates (ADCs).

Benzyloxy carbonyl-PEG3-NHS ester is a polyethylene glycol (PEG) derivative compound utilized as a PROTAC linker in the synthesis of PROTACs [1].

Bis-PEG17-NHS ester is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Biotin-PEG2-NHS ester is a biotinylated polyethylene glycol (PEG)-based linker used in PROTAC synthesis for biotin attachment[1].

N-(m-PEG4)-N'-(biotin-PEG3)-Cy5, a PEG-based PROTAC linker, serves as a valuable component in PROTAC synthesis [1].

m-PEG17-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker used for synthesizing PROTACs [1].

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].