bis-(m-peg8-amido)-hexanoic acid

Bis-(m-PEG8-amido)-hexanoic acid is a polyethylene glycol (PEG)-based linker used in synthesizing proteolysis targeting chimeras (PROTACs) [1].

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.

Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.

m-PEG12-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs.

Bis-CH2-PEG2-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thalidomide-O-amido-PEG-C2-NH2 is a synthesized conjugate formulation designed as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand based on Thalidomide and a linker component commonly used in PROTAC technology.

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

m-PEG4-phosphonic acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

m-PEG-thiol (MW 10000) is a PEG-based linker for PROTACs that joins two critical ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-thiol (MW 5000) is a PEG-based linker used in PROTACs, facilitating the conjugation of essential ligands necessary for PROTAC molecule formation, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Biotin-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker molecule used in the synthesis of PROTACs[1].

m-PEG2-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG21-acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG5-phosphonic acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands necessary for PROTAC molecule formation. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG12-acid is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by connecting two essential ligands and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker used in the development of antibody-drug conjugates (ADC).

Bis-PEG10-acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-Mal-Lysine-PEG4-acid is a PEG-based PROTAC linker used for PROTAC synthesis [1].

Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Bis-PEG13-acid, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-thiol (MW 2000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG4-phosphonic acid ethyl ester is a PEGylation-based linker used in the design and synthesis of PROTACs, which are heterobifunctional molecules that facilitate targeted protein degradation[1].

m-PEG-mal (MW 5000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker extensively used in the synthesis of PROTACs (proteolysis targeting chimeras)[1].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized in synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Bis-PEG4-sulfonic acid is a PEG-based linker for PROTACs, facilitating the conjugation of essential ligands critical for PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG11-acid is a non-cleavable 11-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1] and as a PEG-based linker for PROTAC synthesis [2].

N-(m-PEG4)-3,3-Dimethyl-3H-indole-N'-(acid-PEG3)-benzothiazole is a PEG-based PROTAC linker suitable for synthesizing PROTACs [1].

m-PEG5-phosphonic acid ethyl ester, a polyethylene glycol (PEG)-derived linker, is commonly used in constructing proteolysis targeting chimeras (PROTACs) [1].

PEG4-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative functioning as a linker in PROTAC synthesis, specifically designed for creating proteolysis-targeting chimeras (PROTACs)[1].

m-PEG-Tresyl (MW 5000) is a polyethylene glycol (PEG)-based linker used in proteolysis-targeting chimeras (PROTACs), facilitating the joining of two essential ligands necessary for forming PROTAC molecules. This linker promotes selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

m-PEG-NPC (MW 20000) is a PEG-based linker for PROTACs, joining two essential ligands to facilitate the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Biotin-bis-amido-SS-NHS is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs.

Bis-(m-PEG4)-amidohexanoic acid is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-Me-N-bis(PEG4-acid) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

N-(m-PEG4)-N'-(PEG4-acid)-Cy5 is a polyethylene glycol (PEG)-based PROTAC linker used in the synthesis of PROTACs[1].

NH-bis(PEG3-acid) is a PEG-based linker utilized in PROTACs, connecting two essential ligands crucial for creating PROTAC molecules. This linker leverages the ubiquitin-proteasome system within cells to enable selective protein degradation.

m-PEG9-acid, a PEG-based linker for PROTACs, integrates two essential ligands vital for PROTAC molecule formation, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

N-Biotin-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker used for the synthesis of PROTACs [1].

Ald-Ph-amido-PEG24-acid, a polyethylene glycol (PEG)-based linker, is utilized in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

m-PEG-Aminooxy (MW 2000) is a polyethylene glycol (PEG) derived PROTAC linker, primarily used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

N,N'-DME-N,N'-Bis-PEG2-acid is a polyethylene glycol (PEG)-derived linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

m-PEG-triethoxysilane (MW 5000) is a polyethylene glycol-based PROTAC linker suitable for synthesizing PROTACs[1].

m-PEG-azide (MW 10000), a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.