bis-peg5-thiol

Bis-PEG5-thiol is a PEG derivative containing two thiol groups. The thiol groups react with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1,1'-(hydrogen phosphate) is a compound that is a phosphoric acid derivative of compound statins.

1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl] is an antifibrotic agent.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

m-PEG-thiol (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate is a natural product for research related to life sciences. The catalog number is TN3115 and the CAS number is 1269839-24-8.

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood.

Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker employed in PROTAC synthesis[1].

4,4'-(Cyclopent-1-ene-1,2-diyl)bis(5-methylthiophene-2-carbaldehydE) is a useful organic compound for research related to life sciences and the catalog number is T64484.

5-Methyl-1,3,4-thiadiazole-2-thiol is a useful organic compound for research related to life sciences. The catalog number is T66917 and the CAS number is 29490-19-5.

3,5,8,3'-Tetramethoxy-6,7,4',5'-bis(methylenedioxy)flavone is a natural product for research related to life sciences. The catalog number is TN6187 and the CAS number is 82668-93-7.

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides, Protected nucleosides with NH2/OH open

m-PEG-thiol (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized for synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Benzamide, N,N-bis(5-(p-aminophenoxy)pentyl)- is a bioactive chemical.

Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a useful organic compound for research related to life sciences and the catalog number is T67406.

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides,2’-Modified nucleosides; Protected nucleosides with NH2/OH group

m-PEG-thiol (MW 10000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

1-[(5E)-3-O-[(Bis-di-isopropyl amino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil is a Nucleoside Phosphoramidite; Nucleoside Derivative - Phosphorus-containing nucleotide; 5'-Modified nucleoside.

Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene][[5-[(dimethylamino)sulfonyl]-2-(1-methylethoxy-O)phenyl]methylene-C]ruthenium(II) is a useful organic compound for research related to life sciences and the catalog number is T66135.

Nucleosides Derivatives - Protected nucleosides with NH2/OH group

2',3'-Bis-O-(t-butyldimethylsilyl)-5'-O-(4,4'-dimethyltriphenylmethyl)uridine is a nucleoside Derivative - Other modified nucleoside.

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG) based PROTAC linker, primarily utilized for the synthesis of PROTACs[1].

3,5’-Bis(O-t-butyldimethylsilyl)-2’-O-methyl-5-methyl cytidine, a cytidine analog, inhibits DNA methyltransferases (e.g., Zebularine), exhibiting potential anti-metabolic and anti-tumor activities [1].

Thiol-PEG-CH2COOH (MW 5000) is a Polyethylene glycol (PEG) derived link molecule, commonly utilized in the construction of PROTACs, which are bifunctional compounds designed for targeted protein degradation [1].

Ethyl 4-(5-(bis(2-hydroxyethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate is a useful organic compound for research related to life sciences. The catalog number is T65581 and the CAS number is 3543-74-6.

Fluoro-modified nucleoside, halo-nucleoside

PEG-bis-amine (MW 1000) is used to synthesize folate-conjugated polymer micelles that encapsulate the anticancer agent 9-nitrocamptothecin. These folic acid-conjugated polymer micelles effectively deliver insoluble anticancer drugs, evading macrophages and facilitating endocytosis by tumor cells through folate receptors (FR).

Thiol-PEG-CH2COOH (MW 3400) is a Polyethylene Glycol (PEG) derivative employed as a PROTAC linker for PROTAC synthesis[1].

(11aR)-10,11,12,13-Tetrahydro-N,N-bis[(1R)-1-phenylethyl]diindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-amine is a useful organic compound for research related to life sciences and the catalog number is T66952.

4-Chloro-5-iodo-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1024.

3',5'-Bis-O-(triphenylmethyl)uridine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group.

2'-O-Acetyl-3',5'-bis-O-benzoyl-6-aza-xylo uridine is a Nucleoside Derivative - Xylo-nucleoside; 6-Aza-uridine.

5-Amino-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide is a useful organic compound for research related to life sciences. The catalog number is T65482 and the CAS number is 76801-93-9.

1,7-Bis(4-hydroxyphenyl)-5-hydroxyhept-1-en-3-one is a natural product for research related to life sciences. The catalog number is TN5749 and the CAS number is 1426059-89-3.

2,2'-(5-((4H-1,2,4-Triazol-4-yl)methyl)-1,3-phenylene)bis(2-methylpropanenitrile) is a useful organic compound for research related to life sciences. The catalog number is T67043 and the CAS number is 120511-92-4.

2',3'-Bis(O-t-butyldimethylsilyl)-4',5'-Didehydro-5'-deoxyuridine is a Nucleoside Derivative - 5'-Modified nucleoside, Didehydro-nucleoside.

3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine is a Nucleoside, fluoro-modified nucleoside; Arabino-nucleosidde.

3',5'-Bis(O-t-butyldimethylsilyl)-4'-C-hydroxymethyl thymidine is a Nucleoside Derivative - 4'-Modified nucleoside; Protected nucleoside w/NH2/OH open.

3-((3,5-Bis(trifluoromethyl)phenyl)amino)-4-(((1R)-(6-methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)methyl)amino)cyclobut-3-ene-1,2-dione is a useful organic compound for research related to life sciences. The catalog number is T67231 and the CAS number is 1256245-79-0.

Nucleoside Derivatives –Fluoro-modified nucleosides；

2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE is targets the thyroid stimulating hormone receptor (human)

m-PEG-thiol (MW 20000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Nucleoside Derivatives - Fluoro-modified nucleosides, 4-Deoxypyrimidine nucleosides,Arabinonucleosides, 2’-Modified nucleosides

((2S,2'S)-1,1'-((2-Hydroxy-5-methyl-1,3-phenylene)bis(methylene))bis(pyrrolidine-2,1-diyl))bis(diphenylmethanol) is a useful organic compound for research related to life sciences. The catalog number is T67237 and the CAS number is 320714-00-9.

1-[(5E)-3-O-[(Bis-diisopropyl amino)(2-cyano ethoxy)phosphino]-5,6-dideoxy-6-(diethoxy phosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil is a Nucleoside Phosphoramidite; Nucleoside Derivative - Phosphorus-containing nucleotide; 5'-Modified nucleoside.

Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker molecule containing an amine group and a thiol group. It serves as an essential component in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Thiol-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].

3',5'-Bis-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabino-6-azauridine is a Nucleoside Derivative - 6-Aza-uridine; Fluoro-modified nucleoside; Arabino nucleoside.

PEG-bis-amine (MW 8000) is utilized to synthesize folate-conjugated polymeric micelles, encapsulating the insoluble anticancer agent 9-nitrocamptothecin. These folic acid-conjugated polymer micelles serve as efficient carriers that not only evade macrophages but also facilitate the folate receptor (FR)-mediated endocytosis in tumor cells, enhancing drug delivery.