bis-propargyl-peg2

Bis-propargyl-PEG2, a PEG-based PROTAC linker, facilitates the synthesis of PROTACs and demethylvancomycin dimers[1][2].

N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a polyethylene glycol (PEG) derivative designed as a linker for PROTAC synthesis [1].

Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-linked PROTAC linker used in the synthesis of PROTACs[1].

Propargyl-PEG2-N-bis(PEG2) is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs (proteolysis-targeting chimeras).

N-Boc-N-bis(PEG2-propargyl) is a PEG-derived linker used in synthesizing PROTACs [1].

N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-based linker compound intended for the synthesis of PROTACs [1].

N-Me-N-bis(PEG2-propargyl) is a PEG-based linker used in the synthesis of PROTACs [1].

N-(PEG2-Boc)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-based PROTAC linker utilized in the synthesis of PROTACs[1].

N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a polyethylene glycol (PEG) derivative frequently used as a PEG-based linker in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt is a PEG derivative with an amino group and two propargyl groups, which may be useful in developing antibody-drug conjugates [PEG Linkers].

NH-bis(PEG2-propargyl) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-derived linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker used in the synthesis of MT802 and SJF620, which are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively [1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Bis-propargyl-O-PEG17 is a PEG-based linker for PROTACs that connects two essential ligands, crucial for forming PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Bis-propargyl-PEG9 is a PEG-based PROTAC linker employed in the synthesis of PROTACs. It is specifically utilized to synthesize the bivalent ligands of estrogen receptor[1].

2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker used in the synthesis of PROTACs[1].

Bis-propargyl-PEG4 is a PEG-based PROTAC linker utilized in PROTAC synthesis and specifically employed in the synthesis of demethylvancomycin dimers[1][2].

Bis (2-bromoethyl) ether, an alkyl chain-derived PROTAC linker, facilitates the synthesis of PROTACs.

Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Bis-propargyl-PEG5 serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs. This chemical compound is particularly employed in the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity[1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker, incorporating a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for PROTAC technology applications.

Bis-propargyl-PEG10 is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

Bis-propargyl-PEG8 (compound 16e) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a polyethylene glycol (PEG) based PROTAC linker used for synthesizing PROTACs[1].

Bis-propargyl-PEG12 is a PEG-based linker for PROTACs [Proteolysis Targeting Chimeras] that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

(2-Pyridyldithio)-PEG4-propargyl is a polyethylene glycol (PEG)-based linker engineered for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

2-Amino-1,3-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based linker utilized for PROTAC synthesis[1].

Bis-propargyl-PEG3 is a PEG-based PROTAC linker utilized for the synthesis of PROTACs. It is also employed in the synthesis of antiplasmodial zinc-dipicolylamine (ZnDPA) complexes[1] [2].

N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-based linker extensively used in the synthesis of PROTACs (proteolysis targeting chimeras)[1].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized in synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Bis-propargyl-PEG7 is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). It is particularly employed for the synthesis of polymer-linked multimers of guanosine-3',5'-cyclic monophosphates[1].

Bis-propargyl-PEG13 is a PEG-based linker for PROTACs, facilitating the joining of two essential ligands necessary for creating PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Bis-propargyl-PEG11, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a polyethylene glycol (PEG)-based linker designed for constructing PROTACs.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Bis-propargyl-PEG6 is a polyethylene glycol (PEG) derivative commonly employed as a PEG-based PROTAC linker during the synthesis of PROTACs. Its application includes the generation of polymer-linked multimers of guanosine-3', 5'-cyclic monophosphates[1].

Bis-propargyl-PEG1, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.