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Results for "

bno-peg1-ch2cooh

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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BnO-PEG1-CH2COOH
T1469793206-09-8
BnO-PEG1-CH2COOH is a PEG-based linker for PROTACs that connects two essential ligands, critical for forming PROTAC molecules, and facilitates selective protein degradation using the ubiquitin-proteasome system within cells.
  • Inquiry Price
7-10 days
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(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl
T179121835705-61-7
(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].
  • $61
5 days
Size
QTY
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH
T179032351103-63-2
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized E3 ligase ligand-linker conjugate, incorporating the cereblon ligand from Pomalidomide and a linker used in PROTAC technology. It facilitates targeted protein degradation by modulating E3 ligase activity, thereby enabling the selective elimination of specific proteins of interest.
  • $46
5 days
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QTY
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate
T186532127875-65-2
S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione-cleavable compound used for attaching monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs), specifically referring to the Alkyl-Chain composition of the linker portion of these molecules [1].
  • $77
5 days
Size
QTY
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2
T400942435572-48-6
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.
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DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000)
T17847
DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].
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PROTAC VEGFR-2 degrader-1
T745172601594-19-6
PROTAC VEGFR-2 Degrader-1 (PROTAC-1), a specific degrader of PROTAC VEGFR-2, demonstrates minimal inhibition of VEGFR-2 (IC50 > 1 μM) and exhibits low anti-proliferative effects on EA.hy926 cells (IC50 > 100 μM) [1].
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BCL-xL/BCL-2 ligand 1
T858142941091-91-2
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Thalidomide-O-amido-PEG1-(C1-​PEG)2-C2-NH2
T17917
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized E3 ligase ligand-linker, incorporating a cereblon ligand based on Thalidomide and a 3-unit PEG linker, specifically designed for PROTAC technology applications.
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6-O-2-Propyn-1-yl-D-galactose
T17342881895-59-6
6-O-2-Propyn-1-yl-D-galactose functions as an irreversible glycolinker, facilitating the attachment of cytotoxic drugs for applications in antibody-drug conjugation (ADC).
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