boc ypgflt(o tbu)

Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.

Boc-NH-O-C1-NHS ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

N-Boc-O-tosyl hydroxylamine serves as a nitrogen source for the N-amination of aryl and alkyl amines.

Lys(CO-C3-p-I-Ph)-O-tBu, a pharmacokinetic modifier (PK modifier), enhances the pharmacokinetic properties of PSMA ligand molecules by increasing their residence time in plasma through improved binding to albumin and reducing absorption by the salivary glands, potentially extending the active compound's half-life. Moreover, Ac-PSMA-trillium is an effective PSMA-targeting compound for various biological applications when modified with different radioactive isotopes. When labeled with 111 In, it serves as a DOTA chelating agent and imaging agent. Alternatively, when labeled with 225 Ac, it acts as a Macropa chelator for targeted radionuclide therapy (TRT) in researching metastatic castration-resistant prostate cancer (mCRPC) [1] [2].

Boc-D-Ser(tBu)-OH, an amino acid derivative, has a wide range of applications in life science-related research.

Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC linker used for the EED-targeted PROTAC [1].

(S,R,S)-AHPC-O-Ph-PEG1-NH-Boc (VH032-O-Ph-PEG1-NH-Boc) is an E3 ligase ligand-linker conjugate designed for targeting the EED protein in PROTAC applications[1].

Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a chemical compound primarily used as a linker in PROTAC applications, facilitating the connection between a specific tyrosine kinase inhibitor (TKI) and the E3 recruiting ligand.

Boc-Tyr(tBu)-OH (catalog number T64784, CAS number 47375-34-8) is a valuable organic compound for life sciences research.

Thalidomide-O-C8-Boc is a Cereblon ligand derived from Thalidomide, primarily employed in the recruitment of CRBN protein. This ligand can be linked to a protein ligand via a linker to create PROTACs.

Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized conjugate functioning as an E3 ligase ligand-linker, incorporating the cereblon ligand derived from Thalidomide and a linker, and is utilized in the synthesis of PROTAC BET degraders.

Propargyl-PEG4-O-C1-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Tos-O-C4-NH-Boc is an alkyl ether-based linker used for synthesizing PROTACs [including BSJ-03-204].

Thalidomide-O-PEG4-Boc is a PEG-based PROTAC linker utilized in PROTAC synthesis [1].

Hydroxy-PEG4-O-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.