bodipy fl vh 032

BODIPY FL VH032 is a high-affinity VHL fluorescent probe (Kd= 3.01 nM) with application in time-resolved fluorescence resonance energy-transfer (TR-FRET) assays for high-throughput identification and characterization of VHL ligands. BODIPY FL VH032 consists of a derivative of von Hippel-Lindau (VHL) ligand VH 032 and a fluorophore BODIPY FL(with excitation peak at 504 nm and emission peak at 520 nm), joined by a polyethylene glycol (PEG) 4 linker. The BODIPY FL VH032 VHL TR-FRET signal is stable through the 90 - 300 min incubation time, and theTR-FRET binding assay is sensitive, selective and resistant to assay interference. BODIPY FL VH032 also exhibits high VHL affinity in a fluorescence polarization (FP) assay. Excitation maximum ~ 504 nm; emission maximum ~ 520 nm.

BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with binding affinities of Ki: 14.5 nM for α1a-AR and Ki: 43.3 nM for α1b-AR, used to study subcellular localization differences in α1-adrenoceptor subtypes.

BODIPY FL Hydrazide is a green-fluorescent dye that reacts with aldehyde or ketone groups on polysaccharides and glycoproteins to form a reversible Schiff base, which can be stabilized through reduction with agents such as sodium borohydride or sodium cyanoborohydride. Its excitation and emission wavelengths are λ ex =495 nm and λ em =516 nm, respectively. [1] [2]

BODIPY-FL (BDP FL acid) is a broad-spectrum and effective fluorescent dye that can be used to label probes or primers and is a compound for the quantitative detection of specific DNA/RNA based on fluorescence bursts.BODIPY-FL-labelled monoterpenes can be used to detect Gram-positive and Gram-negative bacteria as characteristic and pathogenic fungi.

BODIPY FL Verapamil hydrochloride, a fluorescent dye, serves as a molecular probe for labeling tissues and cells and is a substrate for both ABCB1 and ABCC1 [1] [2].

BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye used to visualize individual cells, with excitation emission wavelengths at 505 nm 512 nm. The Golgi fluorescent probe, a BODIPY-labeled ceramide derivative, is synthesized in the endoplasmic reticulum and transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, enabling specific labeling of the dye [1][2].

BODIPY FL DHPE, a green-fluorescent phospholipid probe, specifically targets and labels the lipid 1,2-dihexadecanoyl-sn-glycero-phosphoethanolamine (DHPE). When labeled, these liposomes can subsequently be internalized through membrane fusion. This compound is particularly useful for studying both membrane surfaces and the process of membrane fusion. (λ ex =505 nm, λ em =511 nm) [1].

BODIPYFL C12 is a BODIPY dye, a small molecule dye with strong ultraviolet absorption ability, a sharp fluorescence peak, and high quantum yield. It is relatively insensitive to environmental polarity and pH and remains stable under different physiological conditions. Due to its structural asymmetry, BODIPY derivatives exhibit various structural products. BODIPY lipid droplet dyes effectively penetrate cell membranes, localize polar lipids, and specifically stain lipid droplets, making them suitable for labeling live and fixed cells [1]. Maximum excitation emission wavelength: 480 508 nm [1].

BODIPY FL C5-HPC, a lipophilic green fluorescent dye (Ex Em: 500 510 nm) [1].

BODIPY FL SSE is a powerful fluorescent dye employed to label primary amines (R-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules. It interacts with primary amines on biomolecules to produce green fluorescence, with excitation and emission wavelengths of 502 nm and 511 nm, respectively [1] [2].

BODIPY FL-X is a green-fluorescent dye with a succinimidyl ester that covalently attaches to proteins, offering high fluorescence quantum yield and minimal pH sensitivity (λ ex =504 nm, λ em =510 nm) [1] [2].

ODIPY FL EDA free base, an amine-based green fluorescent probe, possesses an R-NH2 group able to undergo coupling with aldehydes or ketones, forming reversible Schiff base adducts. These intermediates can be subsequently converted into stable amine derivatives through reduction with agents like sodium borohydride or sodium cyanoborohydride. The compound is applicable in the detection of both modified and normal deoxynucleotides, as well as in illustrating DNA damage and genomic DNA methylation.

BODIPY FL alkyne (BOD FL alkyne) is a green-fluorescent dye with an excitation maximum at 503 nm and an emission peak at 512 nm, exhibiting bright and photostable fluorescence within the fluorescein (FAM) channel. The fluorophore readily undergoes conjugation with various azide-containing molecules through copper-catalyzed Click Chemistry.

BODIPY-FL NHS ester is a luminous, green-emitting fluorophore.

BODIPY FL hydrazide hydrochloride is a versatile dye with multifaceted applications. As a crucial tool in biological experiments, this dye enables the observation and analysis of cell structures, tracking of biomolecules, evaluation of cell functions, differentiation of cell types, detection of biomolecules, examination of tissue pathology, and monitoring of microorganisms. Its use spans across basic scientific research and a broad spectrum of clinical diagnostics. Beyond life sciences, dyes like BODIPY FL hydrazide hydrochloride find extensive use in traditional industries such as textile dyeing and in innovative areas including functional textile processing, food pigments, and dye-sensitized solar cells.

BODIPY FL-C5 NHS Ester, a green-fluorescent dye, reacts with primary amines found in biomolecules including peptides, proteins, modified nucleotides, and biopolymers [1].

BODIPY FL-EDA, a fluorescent dye and an aliphatic-amine analog, efficiently couples with aldehydes and ketones. This compound is utilized in the detection of both modified and normal deoxynucleotides, as well as in assessing DNA damage and genomic DNA methylation [1].

BODIPY FL Ethylamine, a fluorescent dye, forms a reversible Schiff base when it reacts with aldehydes or ketones. This compound can be converted into a stable amine derivative through reduction with either sodium borohydride or sodium cyanoborohydride [1].

BODIPY FL L-Cystine, a thiol-reactive, green-fluorescent dye, is used for labeling membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. The compound exhibits an excitation wavelength (λ ex) of 504 nm and an emission wavelength (λ em) of 511 nm. [1] [2]

BODIPY FL C5 is a green fluorescent fatty acid that can be used as a precursor for synthesizing various fluorescent phospholipids. It is relatively insensitive to the environment and fluoresces in both water-soluble and lipid environments [1].

BODIPY FL Thapsigargin, a potent green fluorescent dye, effectively inhibits intracellular SERCA-type Ca 2+ pumps localized in the sarcoplasmic/endoplasmic reticulum. It is utilized to investigate thapsigargin binding sites in live cells [1] [2]. For storage, it is crucial to protect this compound from light.