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bpiq-ii

" in TargetMol Product Catalog

Inhibitors & Agonists
1

BPIQ-II (hydrochloride)

T36783171179-37-6

BPIQ-II is a linear imidazoloquinazoline that potently inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 8 pM). It is selective for EGFR over other tyrosine and serine threonine kinases, and cellular studies show that BPIQ-II can selectively inhibit EGF-stimulated signal transmission by competitively binding at the ATP site of EGFR.

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$228

35 days

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