cav 2.2 blocker 1

Cav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain.

Cav 2.2 3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker with IC50 values of 1.22 μM for Cav2.2 and 80 μM for Cav3.2, capable of penetrating the central nervous system.

(+)-KCC2 blocker 1 is a selective inhibitor of KCC2 with an IC50 of 0.4 μM.

DMT1 blocker 1 is a blocker of divalent metal transporter 1 (DMT1) with IC50 of 0.64 μM, which is expected to block the absorption of iron by intestinal cells in vivo.

N-type calcium channel blocker-1 is an orally active analgesic agent with a high affinity for functionally blocking N-type calcium channels.

VGSC blocker-1 is a powerful small molecule that serves as a blocker for the neonatal isoform of the VGSC subtype known as Nav1.5 (nNav1.5). It effectively blocks INa peak currents by 34.9% at a concentration of 1 μM, and demonstrates a 0.3% inhibition of cell invasion at the same concentration in the MDA-MB-231 human breast cancer cell line, without compromising cell viability.

TRPV2-selective blocker 1 (compound IV2-1) is a selective inhibitor of the TRPV2 channel, with an IC50 value of 6.3 μM, specifically targeting the TRPV2 channel without affecting TRPV1, TRPV3, or TRPV4 channels, and effectively suppresses TRPV2-mediated calcium influx in macrophages, inhibiting their phagocytic activity [1].

Cav 3.2 inhibitor 1 is a T-type calcium channel inhibitor with low binding affinity for the dopamine receptor (D2 receptor) and can be used in studies of physical and visceral pain.

Werneriachromene; 3-(2.2-Dimethyl-2H-1-benzopyran- is a useful organic compound for research related to life sciences. The catalog number is T123924 and the CAS number is 92632-00-3.

NaV1.2 1.6 channel blocker-1 is a potent inhibitor of NaV1.2 and NaV1.6 channels, exhibiting inhibitory effects on rNaV1.6 and hNaV1.2. This compound can be utilized in the study of generalized epilepsy and movement disorders.

MTDH-SND1 Blocker 1 (Compound C26-A6) serves as an inhibitor targeting the MTDH-SND1 protein, effectively suppressing cancer metastasis [1].

6-Acetyl-5.8-dimethoxy-2.2-dimethyl-2H-1-benzopyra is a useful organic compound for research related to life sciences. The catalog number is T124529 and the CAS number is 62458-48-4.