cobaltic protoporphyrin ix

Cobaltic Protoporphyrin IX chloride (CoPP) is a potent heme oxygenase 1 (HO-1) inducer with antiviral activity that inhibits influenza A virus (IAV) infection by inducing a type I IFN response. mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activities.

Protoporphyrin IX (PPIX) is a tetrapyrrole containing 4 methyl, 2 propionic and 2 vinyl side chains that is a metabolic precursor for hemes, cytochrome c, and chlorophyll.

Mg(II) protoporphyrin IX, essential for chlorophyll synthesis in Chlorella, functions as a negative regulator of nuclear photosynthetic gene expression and is used as a research tool for studying the signaling molecule in plastid-to-nucleus communication.

Cu (II) Protoporphyrin IX functions as a negative control for Zn (II) Protoporphyrin, a heme oxygenase inhibitor. Heme oxygenase is involved in tumor cell resistance to chemotherapy and the regulation of free radical formation, inflammation, and vascular repair.

Cobalt Protoporphyrin IX serves as a potent, specific inducer of heme oxygenase-1 (HO-1) and demonstrates broad-spectrum antiviral effects against Influenza A virus (IAV) [1].

Mn(III) protoporphyrin IX chloride, a metalloporphyrin, at 10 µM concentration, promotes mRNA expression of δ-aminolevulinate synthase and heme oxygenase (HO) in chick embryo liver cells, critical enzymes for heme biosynthesis and breakdown. It has been used in nanobialys for MRI of fibrin clots in vitro and in the creation of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histidine methyl ester (MnGGH), a metalloporphyrin conjugate with microperoxidase activity.

Ga(III)protoporphyrin-IX, a model for interporphyrin interactions in malaria pigment, possesses potent antibacterial effects against gram-negative, gram-positive, and acid-fast bacteria. It exhibits high solubility in methanol (MeOH) and serves as a malarial pigment analogue for drug development, as well as a potential antibacterial agent.

Mn(II) protoporphyrin IX is a potent intravenous paramagnetic magnetic resonance contrast agent, noted for its strong paramagnetic properties.

Ni(II) protoporphyrin IX is a metalloporphyrin compound characterized by limited propensity for axial ligation and distortion upon binding to [ferrochelatase].

Tin-protoporphyrin IX dichloride (SnPPIX dichloride) is an HO-1) inhibitor with antiviral activity that inhibits dengue and yellow fever viruses.