coumarin boronic acid

Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide.It reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively.

Coumarin boronic acid pinacolate ester (CBE) is a more soluble form of coumarin boronic acid that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide. Peroxynitrite oxidizes CBE into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively.

The combination of Valproic acid with Coumarin-3-carboxylic acid (3-Carboxycoumarin) suppresses the proliferation and migration of lung cancer cells via EGFR VEGFR2 c-Met-Akt-NF-κB signaling pathways; this combination may have a wide therapeutic and or adjuvant therapeutic application in the treatment of lung cancer.

(2-Fluorophenyl)boronic acid is a useful organic compound for research related to life sciences. The catalog number is T66269 and the CAS number is 1993-03-9.

[6-(4-Methylpiperazin-1-yl)pyridin-3-yl]boronic acid hydrochloride salt is an intermediate and building block–boronic acid, heterocyclic compound-pyridine.

Heterocyclic compound-pyridine, intermediate and building block-boronic acid

5-Phenyl-3-pyridine boronic acid is an intermediate and building block–boronic acid, heterocyclic compound-pyridine.