cp465022

CP 465022 hydrochloride is a potent, and selective noncompetitive antagonist of AMPA receptor with anticonvulsant activity. CP 465022 hydrochloride inhibits Kainate-induced response with an IC50 of 25 nM in rat cortical neurons.

CP-465022 Maleate is a potent, selective, noncompetitive AMPA receptor antagonist with anticonvulsant activity, effectively countering the Kainate-induced response in rat cortical neurons with an IC50 of 25 nM, making it a valuable instrument for studying the involvement of AMPA receptors in various physiological and pathophysiological processes [1] [2].