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cr 6086

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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CR-6086
T707181417742-86-9
CR6086 is a novel, potent EP4 antagonist showing favourable immunomodulatory properties, striking DMARD effects in rodents, and anti-inflammatory activity targeted to immune-mediated inflammatory diseases and distinct from the general effects of cyclooxygenase inhibitors. CR6086 showed selectivity and high affinity for the human EP4 receptor (Ki = 16.6 nM) and functioned as a pure antagonist (half-maximal inhibitory concentration, 22 nM) on PGE2-stimulated cAMP production.
  • $2,120
8-10 weeks
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ArgTX-48 TFA
T707161418874-74-4
ArgTX-48 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs.
  • $1,820
8-10 weeks
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