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Results for "
csrm 617 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists3
CSRM617 hydrochloride
CSRM617 hydrochloride(787504-88-5 Free base)
T10896L1353749-74-2In house
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor), with a Kd of 7.43 µM in SPR assays, directly binding to the OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP and is well tolerated in the mouse model of prostate cancer [1].
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GNE-617 hydrochloride
T629382070014-99-0
GNE-617 hydrochloride is a selective inhibitor of NAMPT, effectively inhibiting NAMPT activity with an IC50 of 5 nM.
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GNE-617 hydrochloride (1362154-70-8 free base)
GNE-617 hydrochloride
T22801
GNE-617 hydrochloride is a potent and competitive inhibitor of nicotinamide phosphoribosyltransferase (IC50: 5nM). GNE-617 hydrochloride reduces the NAD levels in a > 95% reduction in both NAPRT1-deficient and NAPRT1-proficient cell lines and exerts (EC50
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