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By Target- Autophagy
- Dehydrogenase(1)
- Endogenous Metabolite(1)
- Glucocorticoid Receptor(1)
- Hydroxylase(1)
- P450(1)
- Somatostatin(1)
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Results for "
cushing's
" in TargetMol Product Catalog- Inhibitors & Agonists10
- Peptide Products2
- Natural Products1
Pasireotide Acetate
Cited
TP2207396091-76-2
Pasireotide (SOM230) acetate is a long-acting cyclohexapeptide growth hormone inhibitory hormone analog with antisecretory, antiproliferative, and proapoptotic activities.Pasireotide (SOM230) acetate inhibits the secretion of GH, IGF-I, and ACTH, and can be used in the study of acromegaly and Cushing's disease. Pasireotide (SOM230) acetate also enhances the agonist activity of growth inhibitory receptors, with pKi of 8.2, 9.0, 9.1, <7.0 and 9.9 for sst1, 2, 3, 4 and 5, respectively.
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CitedPasireotide
SOM 230,SOM 320
T12370396091-73-9
Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (subtypes sst1 2 3 4 5, pKi=8.2 9.0 9.1 <7.0 9.9 respectively).
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