cyclo(l-phe-l-pro)

Cyclo(L-Phe-L-Pro) shows broad-spectrum antibacterial and antifungal activities. Cyclo(L-Phe-L-Pro) exhibits activity against methicillin-resistant S. aureus and Enterococcus raffinosus.

L-ANAP is a polarity-sensitive and genetically encodable fluorescent unnatural amino acid.

BODIPY FL L-Cystine, a thiol-reactive, green-fluorescent dye, is used for labeling membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. The compound exhibits an excitation wavelength (λ ex) of 504 nm and an emission wavelength (λ em) of 511 nm. [1] [2]

4-Methylumbelliferyl-α-L-fucopyranoside serves as a fluorogenic substrate for α-L-fucosidase, releasing 4-methylumbelliferone (4-ΜU) upon enzymatic cleavage by the enzyme. The fluorescence of 4-ΜU, with excitation/emission maxima at 350/440 nm, respectively, allows for the quantification of α-L-fucosidase activity.

L-ANAP hydrochloride is a polarity-sensitive and genetically encodable fluorescent unnatural amino acid.

L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase.1Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. 1.Izquierdo, M., Lin, D., O’Neill, S., et al.Development of a high-throughput screening assay to identify inhibitors of the major M17-leucyl aminopeptidase from Trypanosoma cruzi using rapidfire mass spectrometrySLAS Discov.25(9)1064-1071(2020)

Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H.1,2Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify trypsin, cathepsin B, and cathepsin H activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. 1.Zimmerman, M., Ashe, B., Yurewicz, E.C., et al.Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substratesAnal. Biochem.78(1)47-51(1977) 2.Brindley, P.J., Kalinna, B.H., Dalton, J.P., et al.Proteolytic degradation of host hemoglobin by schistosomesMol. Biochem. Parasitol.89(1)1-9(1997)

H-L-Photo-lysine hydrochloride, a photo-cross-linker, is a diazirine-containing lysine amino acid. It can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells.

H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA serves as a chromogenic substrate for Pin1, a conserved mitotic peptidyl-prolyl isomerase that recognizes phosphoserine-proline bonds in mitotic phosphoproteins [1] [2].

Biotin-(L-Thyroxine) is a biotinylated L-Thyroxine, a synthetic hormone used in hypothyroidism research. DIO enzymes convert this compound (T4) into the biologically active thyroid hormone, Triiodothyronine (T3) [1].

Ala-Phe-Pro-pNA, a chromogenic substrate of tripeptidyl peptidase, can be utilized to assess tripeptidyl peptidase activity [1].

L-ANAP TFA is a fluorescent unnatural amino acid (Uaa) that is both genetically encodable and sensitive to polarity [1] [2].

Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) serves as a chromogenic substrate for the peptidylprolyl isomerase Pin1. It is utilized to assess Pin1's inhibition by target compounds and to evaluate its catalytic activity, among other applications [1] [2].

L-ANAP hydrochloride is a fluorescent unnatural amino acid (Uaa) that is both genetically encodable and polarity-sensitive.

C6 NBD L-threo-ceramide, a cell-permeable analog of ceramides tagged with the fluorescent group C6 nitrobenzoxadiazole (C6 NBD), is quickly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts.

L-Pyroglutamic acid β-naphthylamide (PYR) is a derivative of glutamic acid.

DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye used as a fluorogenic substrate for aspartyl proteinase from the human malaria parasite [1]. It should be stored protected from light.