dbco-ss-peg-4-biotin

DBCO-SS-PEG4-Biotin, a cleavable, mid-functional ADC linker with a 4-unit PEG moiety, is used in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-S-S-PEG3-biotin is a cleavable reagent for the introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved with reducing agents such as DTT, BME, and TCEP to remove the biotin label. PEG linkers can also be used in the synthesis of PROTACs.

Biotin-PEG3-SS-azide (Biotin-PEG3-amido-SS-amido-azide) is a cleavable ADC linker containing 3-unit PEG and can be used to synthesize antibody-drug conjugates (ADCs).

DSPE-PEG-Biotin (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker suitable for synthesizing PROTACs [1].

Biotin-PEG-triethoxysilane (MW 5000) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

Methyltetrazine-SS-PEG4-Biotin is a cleavable four-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

DBCO-SS-aldehyde is an ADC linker employed for ADC synthesis[1]. This cleavable linker is designed to facilitate the conjugation of antibodies and drugs, resulting in antibody-drug conjugates (ADCs).

Diazo Biotin-PEG3-DBCO is a cleavable, three-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Tetrazine-SS-Biotin, a cleavable ADC linker, finds utility in ADC (antibody-drug conjugate) synthesis [1].

Tetrazine-SS-PEG4-Biotin, a cleavable 4-unit PEG ADC linker, is employed for the synthesis of antibody-drug conjugates (ADCs)[1].

Biotin-PEG-triethoxysilane (MW 2000) is a polyethylene glycol (PEG) derivative functionalized with triethoxysilane and biotin moieties, serving as a PEG-based linker for PROTAC synthesis to facilitate the targeted degradation of proteins of interest.

DBCO-NHCO-PEG12-biotin is a PEG-based linker for PROTACs that connects two essential ligands critical for forming PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

DBCO-Biotin (Azadibenzocyclooctyne-Biotin conjugate) is a PROTAC linker based on the alkyl chain.

DBCO-SS-amine is a cleavable linker essential in ADC synthesis, facilitating the attachment of cytotoxic drugs to antibodies for targeted delivery to cells or proteins. Its cleavable nature allows for controlled drug release, enhancing the effectiveness of ADCs (antibody-drug conjugates).

PC DBCO-PEG3-biotin is a trimeric polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) synthesis, incorporating a cleavable moiety with a dibenzocyclooctyne (DBCO) group and a biotin molecule, enabling efficient drug attachment to antibodies for targeted delivery and controlled release of therapeutic agents in ADCs[1].

Biotin-PEG-amine (MW 3400) is a polyethylene glycol (PEG)-based linker compound used in the synthesis of PROTACs [1].

Biotin-PEG-Biotin (MW 1000) is a PEG-derived PROTAC linker utilized in PROTAC synthesis [1].

DBCO-PEG4-SS-TCO is a cleavable 4-unit polyethylene glycol (PEG) linker crucial for the synthesis of antibody-drug conjugates (ADCs)[1], facilitating the connection of the drug payload to the antibody and enabling targeted drug delivery.

TAMRA-Azide-PEG-biotin is a PEG-based linker for PROTACs, joining two essential ligands. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

NHS-SS-biotin is a cleavable linker essential in ADC synthesis, joining cytotoxic drugs to antibodies for precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

DBCO-NHCO-PEG6-Biotin is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the creation of PROTAC molecules. This linker promotes selective protein degradation by utilizing the ubiquitin-proteasome system [within cells].

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor used as a toxin payload in antibody-drug conjugates, is conjugated via a DBCO-(PEG)3-vc-PAB linker.

Dde Biotin-PEG4-DBCO is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

WSPC Biotin-PEG3-DBCO is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the assembly of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

DBCO-Sulfo-Link-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

Azide-C2-SS-C2-biotin is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biotin-bis-amido-SS-NHS is an alkyl ether-based PROTAC linker used in the synthesis of PROTACs.

DBCO-NHCO-PEG2-Biotin is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.