dm3

DM3 (Maytansinoid DM3) is a maytansine mimic with disulfide or thiol groups, acting as a tubulin inhibitor and serving as the cytotoxic component in antibody-drug conjugates (ADCs).

DM3-SMe, a maytansine derivative and tubulin inhibitor, acts as the cytotoxic component in antibody-drug conjugates (ADCs). It can bind to antibodies through disulfide bonds or stable thioether bonds and demonstrates high in vitro cytotoxic activity with an IC50 of 0.0011.

BDM31827 is an EthR inhibitor.

BDM31369 is an activator of ethionamide.

BDM31343 is an EthR inhibitor, boosting antituberculous activity of ethionamide.