dspe-peg-amine

DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE . It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.1,2,3DSPE-PEG(2000)-amine has also been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications.4It can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles.4,5 1.Sloat, B.R., Sandoval, M.A., Li, D., et al.In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticlesInt. J. Pharm.409(1-2)278-288(2011) 2.Abd-Rabou, A.A., Bharali, D.J., and Mousa, S.A.Taribavirin and 5-fluorouracil-loaded pegylated-lipid nanoparticle synthesis, p38 docking, and antiproliferative effects on MCF-7 breast cancerPharm. Res.35(4)76(2018) 3.Affram, K., Udofot, O., Singh, M., et al.Smart thermosensitive liposomes for effective solid tumor therapy and in vivo imagingPLoS One12(9):e0815116(2017) 4.Wang, L.-S., Wu, L.-C., Lu, S.-Y., et al.Biofunctionalized phospholipid-capped mesoporous silica nanoshuttles for targeted drug delivery: Improved water suspensibility and decreased nonspecific protein bindingACS Nano4(8)4371-4379(2010) 5.Wen, X., Wang, K., Zhao, Z., et al.Brain-targeted delivery of trans-activating transcriptor-conjugated magnetic PLGA/lipid nanoparticlesPLoS One9(9):e106652(2014)

DSPE-PEG(2000)-Amine is a useful organic compound for research related to life sciences and the catalog number is T64566.

DSPE-PEG-Amine (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker, serving as a crucial component in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

DSPE-PEG-Amine (MW 3400), a polyethylene glycol (PEG)-based PROTAC linker, serves as a crucial component in the synthesis of PROTACs[1].

DSPE-PEG-OH (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

DSPE-PEG-Cyanur, a PEG derivative with a cyanur (cyanuric) functional group, is utilized for the PEGylation of proteins under mild basic conditions and serves as a component for nanostructured lipid carriers [1] [2].

Amine-PEG-amine (MW 5000) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Boc-NH-PEG-amine (MW 3400) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

Amine-PEG-amine (MW 20000) is a polyethylene glycol (PEG)-based linker compound utilized in the synthesis of PROTACs.

Azide-PEG-amine (MW 2000) is a Polyethylene Glycol (PEG)-derived linker compound used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker used for the synthesis of PROTACs [1].

MPEG-2000-DSPE sodium is a phospholipid PEG conjugate with hydrophilicity and hydrophobicity. It is utilized in liposome synthesis to enhance the hydrophilicity of liposomes, thereby prolonging their circulation in the bloodstream. This compound is commonly employed for the investigation of anticancer and antimalarial agents.

DSPE-PEG-NHS (MW 3400), a pegylated phospholipid derivative, is utilized in the formulation of liposomes or lipid nanoparticles within targeted drug delivery systems, including DNA or mRNA vaccines.

Amine-PEG-amine (MW 35000), a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1].

Azide-PEG-amine (MW 3500) is a polyethylene glycol (PEG) linker compound, designed for the synthesis of proteolysis targeting chimeric molecules (PROTACs)[1].

Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].

HO-PEG-amine (MW 2000) is a PEG-based linker essential for constructing PROTAC molecules. It connects two critical ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

HO-PEG-amine (MW 1000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system in cells.

Azide-PEG-amine (MW 5000) is a polyethylene glycol (PEG)-derived linker compound with azide functionality, primarily utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Boc-NH-PEG-amine (MW 2000) is a polyethylene glycol (PEG) linker utilized in PROTAC synthesis[1].

Biotin-PEG-amine (MW 3400) is a polyethylene glycol (PEG)-based linker compound used in the synthesis of PROTACs [1].

DSPE-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker. It serves as an essential component in the synthesis of PROTACs, enabling the targeted degradation of specific proteins[1].

HO-PEG-amine (MW 3400) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

DSPE-PEG-Maleimide (MW 2000) is a PEG compound which composed of DSPE and maleimide groups. DSPE-PEG-Maleimide (MW 2000) can be used for compose liposomes [1] .

PEG-bis-amine (MW 1000) is used to synthesize folate-conjugated polymer micelles that encapsulate the anticancer agent 9-nitrocamptothecin. These folic acid-conjugated polymer micelles effectively deliver insoluble anticancer drugs, evading macrophages and facilitating endocytosis by tumor cells through folate receptors (FR).

DSPE-PEG-SH (MW 2000), a pegylated phospholipid featuring a reactive thiol group for forming covalent thioether linkages with maleimide, is an amphiphilic polymer capable of self-assembling into lipid bilayers in aqueous solutions. It is utilized in encapsulating agents within drug delivery systems, including mRNA vaccines.

DSPE-PEG-Folate (Mw 3350), a derivative of PEG with folic acid content, exhibits targeting capability by binding to folate receptors on cancer cells. It forms micelles/lipid bilayers, facilitating its use in targeted drug delivery system research [1] [2] [3].

DSPE-PEG-Carboxylic Acid, a phospholipid polyethylene glycol (PEG) conjugate, facilitates the targeted delivery of agents and genes [1].

DSPE-PEG-Maleimide is a useful organic compound for research related to life sciences and the catalog number is T64567.

DSPE-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG)-based linker molecule specifically designed for synthesizing protein-targeting chimeras (PROTACs)[1].

Amine-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in PROTAC synthesis, facilitating targeted protein degradation [1].

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

DSPE-PEG-Maleimide (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amine-PEG-thiol (MW 2000) is a PEG-based PROTAC linker used in PROTAC synthesis [1].

DSPE-PEG-Biotin (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

DSPE-PEG, a phospholipid-polymer conjugate, serves as an effective material in drug delivery applications. It is integral to the formulation of nanocarriers designed for prolonged blood circulation, enhanced stability, and improved encapsulation efficiency [1].

DSPE-PEG-Folate (MW 5000), a derivative of polyethylene glycol (PEG) integrated with folic acid, demonstrates a specific targeting ability by binding to folate receptors on cancer cells. This compound forms micelles/lipid bilayers, facilitating its application in targeted drug delivery system research [1] [2].

DSPE-PEG Carboxylic Acid Sodium (MW 2000), a PEG-lipid, facilitates the formation of micelle nanoparticles for drug delivery and extends the blood circulation time of liposomes [1].

DSPE-PEG-PDP, a phospholipid-polyethylene glycol (PEG) conjugate, is utilized in drug delivery applications [1].

Amine-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

HO-PEG-amine (MW 10000), a polyethylene glycol (PEG) derivative, is utilized as a PROTAC linker for the synthesis of PROTACs[1].

HO-PEG-amine (MW 5000) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Biotin-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative commonly used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Amine-PEG-thiol (MW 3400) is a polyethylene glycol (PEG)-based linker with both an amine group and a thiol group, crucial in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

PEG-bis-amine (MW 8000) is utilized to synthesize folate-conjugated polymeric micelles, encapsulating the insoluble anticancer agent 9-nitrocamptothecin. These folic acid-conjugated polymer micelles serve as efficient carriers that not only evade macrophages but also facilitate the folate receptor (FR)-mediated endocytosis in tumor cells, enhancing drug delivery.