dynole 34 2

Dynamin I inhibitor

COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer toxicity during experiments in mice.

GLP-2 (1-34) (human), a polypeptide secreted from the intestine shortly after eating, is utilized in research related to bone remodeling processes [1].

SARS-CoV-2-IN-34 (S-20-1) is a broad-spectrum pan-coronavirus (CoV) fusion inhibitor capable of penetrating the blood-brain barrier and demonstrating extensive inhibitory activity against both pseudotyped and authentic SARS-CoV-2, as well as pseudotyped variants of concern (VOCs). It exhibits high affinity for the receptor-binding domain (RBD) in the S1 and the heptad repeat 1 (HR1) domain in the S2 of the SARS-CoV-2 spike (S) protein, making it a valuable tool for infection research [1].