endo bcn peg4 pfp ester

Endo-BCN-PEG4-PFP ester is a polyethylene glycol (PEG) derivative, specifically designed as a linker for proteolysis-targeting chimeras (PROTACs) [1].

N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).

Bis-PEG23-endo-BCN, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

Bis-PEG2-PFP ester is a non-cleavable 2-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, Bis-PEG2-PFP ester serves as a PEG-based linker for the synthesis of proteolysis targeting chimeras (PROTACs) [2].

N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs).

APN-PEG4-PFP is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG5-PFP ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

endo-BCN-PEG3-acid is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

Acid-PEG3-PFP ester is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-cis-4-hydroxy-D-proline methyl ester (catalog number: T66907, CAS number: 114676-69-6) is a valuable organic compound used in life sciences research.

NHPI-PEG4-C2-NHS ester (WO2014185985A1) is a chemical compound employed as a linker in the formation of antibody-drug conjugates (ADC)[1].

6-Maleimidocaproic acid-PFP ester is a hydrocarbon-based PROTAC linker suitable for synthesizing PROTACs [1].

Mal-PEG5-PFP ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N3-PEG3-C2-PFP ester, a 3-unit polyethylene glycol (PEG) linker without cleavable bonds, is commonly used in the synthesis of antibody-drug conjugates (ADCs).

PC Alkyne-PEG4-NHS ester is a cleavable 4-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Endo-BCN-PEG2-PFP ester, a PEG-based linker, serves as a valuable component in PROTAC synthesis[1].

DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

endo-BCN-PEG8-acid, a PEG-based linker, is pivotal for PROTAC molecules, connecting two essential ligands and facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-PEG4-PFP ester is a PEG-based linker for PROTACs, joining two essential ligands and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Hydroxy-PEG2-C2-PFP ester, a PEG Alkyl ether-based PROteolysis TArgeting Chimeric (PROTAC) linker, is suitable for the synthesis of PROTACs.

Biotin-PFP ester, an alkyl ether-based PROTAC linker, serves as a valuable component in the synthesis of PROTACs[1].

BCN-PEG4-OH is a non-cleavable, 4-unit PEG linker essential for synthesizing antibody-drug conjugates (ADCs) [1].

Mal-PEG4-PFP ester is a non-cleavable antibody-drug conjugate (ADC) linker containing a Maleimide moiety, a 4-unit Polyethylene Glycol (PEG) backbone, and a Pentafluorophenyl (PFP) ester.

Bis-PEG2-endo-BCN is a two-unit cleavable polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker used in PROTAC synthesis [1].

(E)-TCO-PEG4-NHS ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker characterized by its PEG composition, crucial in synthesizing various PROTACs, including BI-3663, a selective PTK2 FAK PROTAC. Using cereblon ligands, it targets E3 ligases to degrade PTK2, exhibiting potent inhibitory activity with an IC50 of 18 nM[1].

endo-BCN-PEG12-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NHPI-PEG2-C2-Pfp ester is a noncleavable 2-unit polyethylene glycol (PEG) linker widely used in the synthesis of antibody-drug conjugates (ADCs).

endo-BCN-PEG2-alcohol, a PEG-based linker for PROTACs, facilitates the connection of two essential ligands, critical for the formation of PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG4-phosphonic acid ethyl ester is a PEGylation-based linker used in the design and synthesis of PROTACs, which are heterobifunctional molecules that facilitate targeted protein degradation[1].

Mal-PEG3-PFP ester is a PEG-based linker for PROTACs, facilitating the combination of two essential ligands, thereby crucial in the formation of PROTAC molecules. This linker promotes selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bromoacetamido-PEG4-NHS ester is a PEGylated N-hydroxysuccinimide ester linker designed for PROTAC synthesis, facilitating the creation of protein-targeted chimeras (PROTACs)[1].

Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

endo-BCN-PEG6-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Mal-amido-PEG4-TFP ester, a PEG-based PROTAC linker, finds utility in the synthesis of PROTACs[1].

Diketone-PEG11-PFP ester serves as a PEG-based PROTAC linker for PROTAC synthesis[1].

BCN-PEG4-alkyne is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG4-4-nitrophenyl carbonate, a PEG-derived PROTAC linker, enables the synthesis of PROTACs[1].

Propargyl-O-C1-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker used in antibody-drug conjugation (ADC) to link antibodies with drugs.

APN-PEG4-BCN is a cleavable, four-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

BCN-PEG4-acid is a cleavable four-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Azido-PEG3-S-PEG4-t-butyl ester, a PEG-based PROTAC linker, is used in PROTAC synthesis [1].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized in synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Iodoacetyl-PEG4-NHS ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Hydroxy-PEG3-PFP ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

N3-PEG4-C2-Pfp ester is a noncleavable, four-unit polyethylene glycol linker used in the fabrication of antibody-drug conjugates (ADCs).

NHS-PEG4-(m-PEG4)3-ester is a PEG-based PROTAC linker used for synthesizing PROTACs [1].