enkephalin-met, tyr-o-sulfate

Enkephalin-met, tyr-O-sulfate is a opioid peptide.

Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin) is a naturally occurring endogenous opioid peptide that inhibits tumor growth by binding to the opioid receptor.

Phosphopeptide; binds to the src SH2 domain.

Fmoc-Met(O)-OH is a useful organic compound for research related to life sciences. The catalog number is T66833 and the CAS number is 76265-70-8.

Enkephalin-met, des-tyr(1)- ccauses retrograde amnesia in rats.

(Met(O)35)-Amyloid β-Protein (1-42) is the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution similar to Aβ40. This compound is utilized in Alzheimer’s disease (AD) research [1].

Enkephalin-met, ala(2)- is a synthetic analog of methionine enkephalin.

O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.

Met-Enkephalin-Arg-Phe, a naturally occurring heptapeptide, exhibits analgesic activity [1].

Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid.Ferulic acid 4-O-sulfate relaxes arteries, lowers blood pressure, and resists oxidative stress under conditions of iron overload in mice and HepG2 cells.Ferulic acid 4-O-sulfate is a metabolite of Ferulic acid.

Phenylephrine-3-O-sulfate is metabolite of the α1A-adrenergic receptor agonist phenylephrine formed via sulfation.

O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases.

Enkephalin-met, lys(6)- is an opioid hexapeptide found in adrenal medulla.

18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), is a potent inhibitor of type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) with an IC50 value of 0.10 µM in rat kidney microsome assays. This compound is a substrate for organic anion transporters (OAT) 1 and OAT3, exhibits anti-inflammatory properties, and holds potential for research into pseudohyperaldosteronism [1] [2].

Corticotropin Releasing Factor, ovine [Met(O)21], is a hypothalamic hormone isolated from ovine hypothalamic extracts. It functions by stimulating the secretion of adrenocorticotrophic hormone (ACTH) [1].

Enkephalin-met, a naturally occurring opioid peptide used to regulate the growth of human colon cancer, can be used as an effective negative regulator of human gastrointestinal cancer and may suggest pathways for tumor etiology, progression, treatment and

Resveratrol-3-O-sulfate is a metabolite of resveratrol . In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 μM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 μM, and induces apoptosis at concentrations of 25 and 50 μM. Resveratrol-3-O-sulfate also displaces rosiglitazone from the outer mitochondrial protein mitoNEET (IC50 = 3.36 μM for the human protein), indicating that it binds to the thiazolidine-2,4-dione (TZD) binding pocket.

(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified glucagon exhibiting the same maximum glucose-synthesizing activity in rat hepatocytes as its native form, but with reduced potency, highlighting the importance of methionine in glucagon's attachment to hepatic receptors [1].

Dopamine 3-O-sulfate, primarily found in plasma, serves as a biomarker for identifying aromatic amino acid decarboxylase (AADC) deficiency [1].