ethacrynic acid d-5

Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid D5, is distinguished by its deuterium labeling.

5-Hydroxyindole-3-acetic Acid-d6 is a deuterated compound of 5-Hydroxyindole-3-acetic Acid. 5-Hydroxyindole-3-acetic Acid has a CAS number of 54-16-0. 5-Hydroxyindoleacetic acid (5HIAA) is a breakdown product of serotonin that is excreted in the urine. Serotonin and 5HIAA are produced in excess amounts by carcinoid tumors, and levels of these substances may be measured in the urine to test for carcinoid tumors (NCI).

5-Hydroxy tryptophol β-D glucuronide-d4 is a deuterated compound of 5-Hydroxy tryptophol β-D glucuronide.