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Results for "

flaviviruses-inhibitor-i

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    35
    TargetMol | Activity
  • Peptide Products
    2
    TargetMol | inventory
  • Reagent Kits
    1
    TargetMol | natural
Flaviviruses-Inhibitor-I
T24066392237-10-4
Flaviviruses-Inhibitor-I is several viruses belonging to the family of Flaviviridae inhibitor.
  • $1,520
6-8 weeks
Size
QTY
AHR Inhibitor I-103
T853432247951-12-6In house
AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.
  • $195
In Stock
Size
QTY
Ubiquitin Isopeptidase Inhibitor I, G5
T17192108477-18-5In house
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).
  • $74
7-10 days
Size
QTY
IRAK-1-4 Inhibitor I
T2457509093-47-4
IRAK-1-4 Inhibitor I is a dual inhibitor targeting IRAK1 and IRAK4.
  • $37
In Stock
Size
QTY
TargetMol | Inhibitor Sale
PRL-3 Inhibitor I
T22136893449-38-2
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells.
  • $52
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Glyoxalase I inhibitor 4
T64023250155-72-7
Glyoxalase I inhibitor 4 is a potent inhibitor of glyoxalase I (GLO1) (Ki: 10 nM).
  • $2,140
6-8 weeks
Size
QTY
Topoisomerase I inhibitor 7
T620022408639-81-4
Topoisomerase I inhibitor 7 (Compound 8) is a potent Topoisomerase I inhibitor that significantly reduces tumor growth by up to 79% and extends the lifespan of mice bearing P388 lymphoma transplants by 153%.
  • $1,520
6-8 weeks
Size
QTY
Topoisomerase I inhibitor 8
T62225210346-40-0
Topoisomerase I inhibitor 8, a hexacyclic analogue of camptothecin, is also a potent inhibitor of topoisomerase I and is toxic to tumour cells.
  • Inquiry Price
10-14 weeks
Size
QTY
Topoisomerase I inhibitor 5
T615012513461-95-3
Topoisomerase I inhibitor 5 is an efficient topoisomerase I inhibitor with an IC50 value, effectively disrupting DNA and inhibiting topoisomerase I activity. It induces apoptosis in MCF-7 cells and arrests the cell cycle at the G1 phase, displaying potency in reversing P-gp-mediated resistance to Adriamycin [1].
  • $2,140
6-8 weeks
Size
QTY
Topoisomerase I/II inhibitor 3
T61990
Topoisomerase I II inhibitor 3 (compound 7) is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) that inhibits the PI3K Akt mTOR signaling pathway, subsequently inhibiting cell proliferation, invasion, and migration, and inducing apoptosis. This compound has research value in liver cancer.
  • $1,520
10-14 weeks
Size
QTY
Topoisomerase I inhibitor 9
T809671228150-86-4
Topoisomerase I Inhibitor 9 (compound 3d), a specific inhibitor of leishmanial topoisomerase IB, exhibits antileishmanial activity, demonstrating an IC50 value of 34.81μM against L. donovani promastigotes [1].
  • Inquiry Price
8-10 weeks
Size
QTY
MMP Inhibitor I (trifluoroacetate salt)
T36962
MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively). It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urease, trypsin, α-chymotrypsin, plasmin, and elastase at concentrations up to 4 mM.
  • $345
35 days
Size
QTY
Glyoxalase I inhibitor 2
T626992314467-61-1
Glyoxalase I inhibitor 2 (compound 26) is a potent inhibitor of glyoxalase I (GLO1) with an IC50 of 0.5 μM, and has potential applications in depression and anxiety studies.
  • $1,520
6-8 weeks
Size
QTY
Topoisomerase I inhibitor 4
T617172485135-31-5
Topoisomerase I inhibitor 4 (compound 7a) is a potent inhibitor of topoisomerase I activity, effectively inhibiting the proliferation of various cancer cell lines, including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 μM, 2.09 μM, 1.56 μM, and 1.92 μM, respectively. Thus, Topoisomerase I inhibitor 4 holds promise for cancer research applications [1].
  • $2,140
6-8 weeks
Size
QTY
Glyoxalase I inhibitor 1
T641531622952-07-1
Glyoxalase I inhibitor 1 is a potent inhibitor of glyoxalase I (GLO1) (IC50: 26 nM).
  • $1,520
6-8 weeks
Size
QTY
Human PD-L1 inhibitor I
T395912135542-86-6
Human PD-L1 inhibitor I is a peptide ligand that specifically inhibits the interaction between human PD-L1 and human PD-1, exhibiting a KD value of 3.39 μM, indicating its binding affinity. The presence of Human PD-L1 inhibitor I disrupts their binding, thereby attenuating their respective functions.
  • Inquiry Price
Size
QTY
Topoisomerase I inhibitor 3
T607662588211-50-9
Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2 M phase. Topoisomerase I inhibitor 3 is an inhibitor of topoisomerase I that interact with topoisomerase I-DNA complex [1].
  • $1,520
6-8 weeks
Size
QTY
MMP-9/MMP-13 Inhibitor I
T37172204140-01-2
MMP-9 MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of 0.9 nM for both enzymes. It is over 20 times more selective for MMP-9 MMP-13 than for other MMPs.
  • $822
Backorder
Size
QTY
Topoisomerase I/II inhibitor 4
T63526
Topoisomerase I/II inhibitor 4 is a potent dual inhibitor of topoisomerase I (Topo I) and II (Topo II) with inhibitory effects on cell proliferation, invasion and migration, and induction of apoptosis, and can be used to study hepatocellular carcinoma.
  • $1,520
10-14 weeks
Size
QTY
Topoisomerase I inhibitor 2
T606172588211-44-1
Topoisomerase I inhibitor 2 (ZML-8) is a highly selective DNA topoisomerase I (Top1) inhibitor that impedes Top1 activity, causing DNA damage. It arrests the cell cycle at the G2 M phase and induces apoptosis, exhibiting anti-tumor effects [1].
  • $1,520
6-8 weeks
Size
QTY
MMP-2/MMP-9 Inhibitor I
T21512193807-58-8
MMP-2 MMP-9-IN-1 is a potent, highly selective, and orally bioavailable inhibitor of type IV collagenases [MMP-9 and MMP-2], exhibiting IC50 values of 0.24 μM for MMP-9 and 0.31 μM for MMP-2, which can be used to study cancer.
  • $54
In Stock
Size
QTY
MMP-8 Inhibitor I
T69666236403-25-1
MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.
  • $492
35 days
Size
QTY
Topoisomerase I inhibitor 6
T620942393082-56-7
Topoisomerase I inhibitor 6 (Compound 3) is a potent Topoisomerase I inhibitor that traps the DNA-Top1 cleavage complex and exhibits low cytotoxicity in non-cancerous cell lines, making it valuable for research.
  • $1,520
6-8 weeks
Size
QTY
Glyoxalase I inhibitor 6
T616922455508-19-5
Glyoxalase I inhibitor 6 (Compound 9j) is an inhibitor of glyoxalase I (Glo-I) with an IC50 of 1.13 μM, exhibiting potential as a low-toxicity anticancer agent [1].
  • $98
5 days
Size
QTY
Topoisomerase I/II inhibitor 2
T61045
Topoisomerase I II inhibitor 2 (compound 1a) is a DNA topoisomerase I II dual inhibitor that significantly reduces xenograft tumor growth in a mouse model, indicating its potential use in treating liver cancer. It is a potent topoisomerase inhibitor with IC50 values of 6.83 μM and 9.82 μM for LM9 cells and Huh7 cells [1].
  • $1,520
10-14 weeks
Size
QTY
Glyoxalase I inhibitor 7
T612862455508-31-1
Glyoxalase I inhibitor 7 (Compound 6) is a potent glyoxalase I (Glo-I) inhibitor with an IC50 of 3.65 μM, exhibiting potential as an anticancer agent [1].
  • $1,520
6-8 weeks
Size
QTY
Topoisomerase I inhibitor 11
T875512922723-28-0
    Inquiry
    Inquiry
    Glyoxalase I inhibitor free base
    T11432174568-92-4
    Glyoxalase I inhibitor (free base), a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.
    • $753
    5 days
    Size
    QTY
    Glyoxalase I inhibitor
    T11433221174-33-0
    Glyoxalase I inhibitor, a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.
    • $862
    6-8 weeks
    Size
    QTY
    MMP-9 Inhibitor I
    T37726206549-55-5
    MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-α converting enzyme (TACE) in a dose-dependent manner (IC50 = 0.54 μM). MMP-9 inhibitor I decreases TNF-α secretion stimulated by LPS in BV-2 microglial cells when used at concentrations of 50 and 100 μM.
    • $363
    35 days
    Size
    QTY
    PKCβII Peptide Inhibitor I
    T80070862502-26-9
    PKCβII Peptide Inhibitor I, a specific PKCβII inhibitor, exhibits cardioprotective properties in a rat cardiac ischemia/reperfusion injury model and mitigates vascular endothelial dysfunction [1].
    • Inquiry Price
    Size
    QTY
    Glyoxalase I inhibitor 3
    T615341415388-25-8
    Glyoxalase I Inhibitor 3 (compound 22g), a potent inhibitor of glyoxalase I (GLO1), demonstrates an IC50 of 0.011 μM, indicating significant efficacy. This compound shows promise for research into depression and anxiety [1].
    • $1,520
    8-10 weeks
    Size
    QTY
    Glyoxalase I inhibitor 5
    T611032455508-17-3
    Glyoxalase I inhibitor 5 (Compound 9h) is a potent glyoxalase I (Glo-I) inhibitor with an IC50 of 1.28 μM, showing potential as an anticancer agent [1].
    • $98
    5 days
    Size
    QTY
    β-Secretase Inhibitor I
    T392511818239-19-8
    β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme. This compound exhibits exceptional inhibitory activity while also demonstrating a significant reduction in cardiovascular and liver toxicity.
    • $970
    Backorder
    Size
    QTY
    Topoisomerase I inhibitor 10
    T80968
    Compound 13, a topoisomerase I inhibitor 10, selectively inhibits leishmanial topoisomerase IB and exhibits antileishmanial activity. Specifically, it demonstrates efficacy against L. donovani promastigotes with an IC50 value of 27.91 μM [1].
    • Inquiry Price
    Size
    QTY