fluorescein-thiourea-peg4-azide

Fluorescein-thiourea-PEG4-azide, a PEG-based PROTAC linker, is employed for the synthesis of PROTACs.

TAMRA-Azide-PEG-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azide-PEG-amine (MW 2000) is a Polyethylene Glycol (PEG) derived linker compound utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Fluorescein-thiourea-PEG2-azide is a PEG-derived linker commonly applied for the synthesis of PROTACs[1].

m-PEG-azide (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Pomalidomide 4'-alkylC6-azide, a Pomalidomide-based cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. It is designed to attach to a protein through a linker, enabling the formation of PROTAC [1].

Azide-PEG-azide (MW 20000) is a polyethylene glycol (PEG)-based linker compound utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Azide-PEG-amine (MW 3500) is a polyethylene glycol (PEG) derived linker compound, specifically designed for the synthesis of proteolysis targeting chimeric molecules (PROTACs)[1].

Lenalidomide 4'-alkyl-C5-azide, a functionalized cerebellar ligand designed for PROTAC development, comprises an E3 ligand and an alkyl LC5 ligand featuring terminal azides for coupling with a target protein ligand [1].

m-PEG-azide (MW 20000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Pomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.

Azide-PEG-amine (MW 5000) is a polyethylene glycol (PEG)-derived linker compound with azide functionality, primarily utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Azide-PEG-azide (MW 10000) is a polyethylene glycol (PEG)-based linker for PROTACs synthesis. It serves as an essential component in assembling PROTAC molecules[1].

Azide-PEG-azide (MW 5000) is a polyethylene glycol (PEG)-based linker component used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Pomalidomide 4'-PEG3-azide is an E3 ligase ligand-linker coupling compound containing the cereblon ligand of Pomalidomide and 1 linker for the synthesis of iRucaparib-TP3.

Pomalidomide 4'-PEG5-azide, a cereblon (CRBN) ligand based on Pomalidomide, facilitates the recruitment of CRBN protein. It can be conjugated through a linker to another ligand, forming a proteolysis-targeting chimera (PROTAC) [1].

Azide-PEG-azide (MW 2000) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Azide-PEG-alcohol, a polyethylene glycol (PEG)-based PROTAC linker with a molecular weight of 2000, functions as a versatile option for the synthesis of PROTACs[1].

Lenalidomide 4'-PEG2-azide, a Lenalidomide-derived Cereblon ligand, facilitates the recruitment of CRBN protein. This compound can be tethered via a linker to a protein ligand, enabling the formation of PROTAC [1].

Lenalidomide 4'-alkyl-C3-azide (compound 4a), a chemically modified version of the orally active immunomodulator lenalidomide, is engineered for the synthesis of PROTACs. This compound, serving as a ligand for the ubiquitin E3 ligase cereblon (CRBN), integrates an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-bearing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups [1].

Fluorescein-thiourea-PEG6-acid is a polyethylene glycol (PEG) derived linker commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Thalidomide 4'-ether-PEG1-azide, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein. This compound is capable of being linked to a protein ligand via a linker to construct PROTACs [1].

m-PEG-azide (MW 10000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-azide (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.