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Results for "

folate receptor 2

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    55
    TargetMol | Activity
  • Peptide Products
    2
    TargetMol | inventory
  • Recombinant Protein
    11
    TargetMol | natural
Edg-2 receptor inhibitor 1
T45211195941-38-8
Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).
  • $98
In Stock
Size
QTY
Dopamine D2 receptor agonist-2
T600751610591-93-9
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.
  • $53
In Stock
Size
QTY
TargetMol | Inhibitor Sale
A2B receptor antagonist 2 hydrochloride
T77508724-70-9
A2B receptor antagonist 2 hydrochloride is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).
  • $195
In Stock
Size
QTY
AMPA receptor antagonist-2
T61068732277-05-3
AMPA receptor antagonist-2 is an AMPA receptor antagonist.
  • $117
In Stock
Size
QTY
AMPA receptor modulator-2
T377342034181-36-5In house
AMPA receptor modulator-2 (Example 134) is an AMPA receptor modulator with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS. Patent. WO2016176460.
  • $125
In Stock
Size
QTY
β2AR/M-receptor agonist-2
T722261017857-38-3In house
β2AR/M-receptor agonist-2 is a dual-function compound acting as a muscarinic antagonist and β2 adrenoceptor agonist (MABA). It demonstrates significant activity towards the β2 adrenoceptor with an EC50 of 3.7 nM and exhibits affinity for the human cloned M3 receptor with a Ki of 0.73 nM. This potent bronchodilator holds potential for research in chronic obstructive pulmonary disease (COPD) treatment.
  • $5,100
7-10 days
Size
QTY
Sigma-1 receptor antagonist 2
T129111639220-15-7In house
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of the sigma-1 receptor (σ1 R, Ki = 3.88 nM) compared to the sigma-2 receptor (Ki = 1288 nM).
  • $97
In Stock
Size
QTY
TargetMol | Inhibitor Sale
CB2 receptor agonist 2
T220091314230-75-5In house
CB2 receptor agonist 2 (ZINC72105556) is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor, Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2.
  • $118
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Orexin 2 Receptor Agonist
T31771796565-52-0
Orexin 2 Receptor Agonist (OX2R) is an effective (EC50: 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio: 70) agonist.
  • $41
In Stock
Size
QTY
TargetMol | Inhibitor Sale
GPR34 receptor antagonist 2
T8848907952-06-1
GPR34 receptor antagonist 2 (Tyrosine, N-[(2E)-3-(4'-chloro[1,1'-biphenyl]-4-yl)-1-oxo-2-propen-1-yl]-O-(phenylmethyl)-) is an anti-inflammatory agent.
  • $118
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Protease-Activated Receptor-2, amide
T7513190383-13-2
Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 with an IC50 of 10.4 M.
  • $48
In Stock
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QTY
TargetMol | Inhibitor Sale
EGF Receptor Substrate 2 (Phospho-Tyr5)
T75764
EGF Receptor Substrate 2 (Phospho-Tyr5) is a biologically active peptide derived from an autophosphorylation site (Tyr 992 ) of epidermal growth factor receptor (EGFR).
  • Inquiry Price
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ET receptor antagonist 2
T79574
ET Receptor Antagonist 2 (Compound 16j) is an orally active ET receptor antagonist with an IC50 of 0.22 nM, suitable for pulmonary arterial hypertension (PAH) research. It has been shown to mitigate monocrotaline-induced PAH in a rat model [1].
  • Inquiry Price
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EP2 receptor antagonist-2
T67946615273-95-5
EP2 receptor antagonist-2 (CID891729) is a compound that blocks EP2 receptor activation by PGE2 and reduces lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA).
  • $44
In Stock
Size
QTY
Protease-Activated Receptor-1 antagonist 2
T742661454588-34-1
Protease-Activated Receptor-1 Antagonist 2 is an orally active antagonist of protease-activated receptor-1 (PAR-1), demonstrating significant potency with an IC 50 of 7 nM. It exhibits favorable pharmacokinetic characteristics, making it valuable in cardiovascular disease (CVD) research, including studies on atherosclerosis and restenosis [1].
  • Inquiry Price
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Glucocorticoid receptor agonist-2
T746972166378-92-1
Glucocorticoid receptor agonist-2 (compound 21), a glucocorticoid receptor agonist with an IC50 value of 6.6 nM, serves as an active reference for ABBV-3373 [1] and is instrumental in the synthesis of anti-inflammatory ADC molecules.
  • Inquiry Price
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Dopamine D4 receptor ligand 2
T86295219125-63-0
  • Inquiry Price
10-14 weeks
Size
QTY
NMDA receptor antagonist 2
T40999875898-41-2
NMDA receptor antagonist 2 is a highly potent and orally active NR2B subtype-selective antagonist of the N-methyl-D-aspartate (NMDA) receptor, with an IC50 of 1.0 nM and a Ki value of 0.88 nM. This compound is valuable in scientific investigations of neuropathic pain and Parkinson’s disease.
  • $970
Backorder
Size
QTY
Orexin 2 Receptor Agonist 2
T395612114324-60-4
Orexin 2 Receptor Agonist 2 (ORA-2) is a specific agonist for the orexin 2 receptor.
    7-10 days
    Inquiry
    A2B receptor antagonist 2
    T37793784-90-7
    A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).
    • $38
    1-2 weeks
    Size
    QTY
    GPR109 receptor agonist-2
    T78100957129-38-3
    Compound 5, a selective GPR109a agonist, exhibits a pEC50 value of 5.53 [1].
      8-10 weeks
      Inquiry
      EP4 receptor agonist 2
      T84402493035-81-7
      EP4 receptor agonist 2 (compound 31) is a potent EP4 receptor agonist, demonstrating an EC50 value of 0.8 nM and K_i values of >100,000, 38,000, and 3.1 nM for the EP2, EP3, and EP4 receptors, respectively [1].
      • Inquiry Price
      8-10 weeks
      Size
      QTY
      5-HT6/5-HT2A receptor ligand-2
      T612202411088-16-7
      Compound 42, a 5-HT6/5-HT2A receptor ligand-2, serves as a dual antagonist for the 5-HT6 and 5-HT2A receptors with Ki values of 25 nM and 32 nM, respectively. This brain-penetrant compound exhibits pro-cognitive properties [1].
      • $1,520
      6-8 weeks
      Size
      QTY
      Adenosine receptor inhibitor 2
      T620182550401-76-6
      Adenosine receptor inhibitor 2 (compound 14b) is a potent inhibitor of AR (adenosine receptor), exhibiting dual affinity towards A1 A2A ARs with higher affinity for A1- than A2A AR, and Ki values of 52.2 nM for A1 AR and 167 nM for A2A AR.
      • $1,520
      6-8 weeks
      Size
      QTY
      S1p receptor agonist 2
      T625171354908-17-0
      S1P receptor agonist 2 (compound 1) is a selective agonist of the S1P5 receptor, exhibiting higher selectivity than for S1P1 and or S1P3 receptors. It is useful in the endogenous SIP signaling system and for mitigating or preventing central nervous system (CNS) diseases, including neurodegenerative diseases.
      • $2,140
      8-10 weeks
      Size
      QTY
      EGF Receptor Substrate 2 Phospho-Tyr5
      TP1807
      EGF Receptor Substrate 2 (Phospho-Tyr5) is a biologically active peptide derived from an autophosphorylation site (Tyr992) of EGFR.
      • $85
      Backorder
      Size
      QTY
      Androgen receptor degrader-2
      T806472616553-33-2
      Androgen Receptor Degrader-2 (Compound 9) is a potent degrader of androgen receptors, with potential application in cancer research [1].
      • Inquiry Price
      8-10 weeks
      Size
      QTY
      Ghrelin receptor full agonist-2
      T402342602452-73-1
      Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist.
      • $970
      Backorder
      Size
      QTY
      Dopamine D3 receptor antagonist-2
      T62946
      Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor-selective compound (Ki=2.16 nM) that exhibits potential therapeutic effects in CNS disorders.
      • $1,520
      10-14 weeks
      Size
      QTY
      Estrogen receptor antagonist 2
      T632772735803-90-2
      Estrogen receptor antagonist 2 is a selective down-regulator of the estrogen receptor, with research potential for breast cancer disease. Estrogen (E2) and estrogen alpha receptor (ERα) are important drivers of breast cancer development.
      • $2,140
      6-8 weeks
      Size
      QTY
      μ opioid receptor agonist 2
      T620252671755-38-5
      μ opioid receptor agonist 2 (Compound H-3) is a MOR receptor agonist used for research on pain and pain-related diseases.
      • $2,140
      6-8 weeks
      Size
      QTY
      A2A receptor antagonist 2
      T63326
      A2A receptor antagonist 2 is a highly selective and potent antagonist of the adenosine A2Areceptor (IC50: 8.3 nM).
      • $1,520
      10-14 weeks
      Size
      QTY
      GABAA receptor agent 2 TFA
      T624261781880-44-1
      GABAA receptor agent 2 TFA is a potent, high-affinity GABAA receptor antagonist with an IC50 of 24 nM [human α1β2γ2GABAA-expressing tsA201 cells] and a Ki of 28 nM [rat GABAA receptor]. GABAA receptor agent 2 TFA has no effect on four human GABA transport proteins [hGAT-1, hBGT-1, hGAT-2, and hGAT-3].
      • $2,140
      8-10 weeks
      Size
      QTY
      P2X7 receptor antagonist-2
      T61566851269-75-5
      P2X7 receptor antagonist-2 is a highly potent inhibitor of the P2X7 receptor, with a pIC50 value range of 6.5-7.5 and demonstrated efficacy in combating neuroinflammation [1].
      • $1,520
      6-8 weeks
      Size
      QTY
      NK1 receptor antagonist 2
      T72224579475-17-5
      NK1 Receptor Antagonist 2, a compound targeting the NK1 receptor, holds potential for tinnitus and hearing loss research.
      • $2,570
      10-14 weeks
      Size
      QTY
      Glucocorticoid receptor-IN-2
      T635392664932-65-2
      Glucocorticoid receptor-IN-2 is a selective regulator of the glucocorticoid receptor (GR) and exhibits anti-inflammatory activity. IC50: 0.171 nM) and also has some transcriptional activating effect on MMTV (EC50: 0.94 nM).
      • $1,520
      6-8 weeks
      Size
      QTY
      EP4 receptor antagonist 2
      T631001965316-82-8
      EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor, with an IC50 of 7.8 nM, and exhibits antitumor effects.
      • $2,140
      10-14 weeks
      Size
      QTY
      Sigma-2 receptor antagonist 1
      T168831802632-22-9
      Sigma-2 receptor antagonist 1 is an antagonist of the sigma-2 (σ-2) receptor.
      • $2,508
      5 days
      Size
      QTY
      Glucagon receptor antagonists-2
      T11414202917-18-8
      Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist.
      • $756
      6-8 weeks
      Size
      QTY
      NMDA receptor modulator 2
      T605522758255-05-7
      NMDA receptor modulator 2 (Compound 1) is a potent NMDA receptor modulator suitable for neurological disorder research [1].
      • $1,520
      6-8 weeks
      Size
      QTY
      Protease-Activated Receptor-1 antagonist 2
      T64285
      Protease-Activated Receptor-1 antagonist 2 is a selective, orally active PAR-1 antagonist (IC50: 7 nM) with favorable pharmacokinetic properties, suitable for cardiovascular disease (CVD) research such as atherosclerosis and restenosis studies.
      • $1,520
      10-14 weeks
      Size
      QTY
      Glucocorticoid receptor agonist-2 Ala-Ala-Mal
      T778692166376-64-1
      Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) serves as a precursor for synthesizing anti-inflammatory antibody-drug conjugate (ADC) molecules and acts as an active reference for ABBV-3373 [1].
      • Inquiry Price
      8-10 weeks
      Size
      QTY
      CB2 receptor antagonist 2
      T82772
      Compound 39, also known as CB2 receptor antagonist 2, is a potent CB2 antagonist exhibiting an IC50 of 0.33 μM. It engages in strong interactions with residues L17, W6.48, V6.51, and C7.42 [1].
      • Inquiry Price
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      5-HT2A receptor agonist-2
      T61507528525-37-3
      5-HT2A receptor agonist-2 is a potent compound that acts as an agonist on the serotonin 5-HT2 receptor, specifically stimulating the 5-HT 2A, 5-HT 2B, and 5-HT 2C receptors with EC50 values of 1.7 nM, 0.58 nM, and 0.50 nM, respectively [1].
      • $1,520
      6-8 weeks
      Size
      QTY
      TP receptor antagonist-2
      T875551448452-22-9
      • Inquiry Price
      10-14 weeks
      Size
      QTY
      Glucocorticoids receptor agonist 2
      T40697614761-20-5
      Glucocorticoid receptor agonist 2 is a highly effective anti-inflammatory compound, derived from arylpyrazole, that actively binds to and activates the glucocorticoid receptor. This compound exhibits potent anti-inflammatory properties without disrupting insulin secretion.
      • Inquiry Price
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      CCK-B Receptor Antagonist 2
      T10707155412-88-7
      CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin CCK-B (IC50: 0.43 nM). It also inhibits gastrin CCK-A activity (IC50: 1.82 μM).
      • $446
      6-8 weeks
      Size
      QTY
      Mu opioid receptor antagonist 2
      T62766
      Mu opioid receptor antagonist 2 (compound 25) is a potent and selective mu opioid receptor (MOR) antagonist that permeates the blood-brain barrier (Ki: 0.37 nM, EC50: 0.44 nM), and can be used to study opioid use disorder (OUD).
      • $1,520
      10-14 weeks
      Size
      QTY
      Estrogen receptor β antagonist 2
      T623112580941-14-4
      Estrogen receptor β antagonist 2 is a selective and potent estrogen receptor β (ERβ) antagonist, with an IC50 of 109.10 μM for ERα and 0.63 μM for ERβ.
      • $1,520
      6-8 weeks
      Size
      QTY
      GABAA receptor agonist 2
      T61625
      GABAA receptor agonist 2 (compound 4c) is a highly potent compound that exhibits anti-depressive properties in classical mouse models of depression, such as the FST and TST. By binding to the GABA binding site on the GABAA receptor, it produces GABAergic effects. Notably, compound 4c holds promise for depression research [1].
      • $1,520
      10-14 weeks
      Size
      QTY