glucosinolate

11-(Methylsulfinyl)undecyl glucosinolate is an aliphatic glucosinolate, characterized by the presence of a sulfurous functional group attached to an undecyl side chain.

Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.

Glucoarabin, a bioactive glucosinolate, upregulates the phase II detoxification enzyme quinone reductase (NQO1) in Hepa1c1c7 cells when hydrolyzed (hGSL 9), without affecting cytochrome P450 (CYP) 1A1 activity [1].

Glucobrassicin (potassium), a glucosinolate (GSL) derived from wild carrot (Raphanus raphanistrum L.), is utilized in biological fumigation and allelopathy studies for weed control [1].

Glucobrassicanapin (4-Pentenylglucosinolate) potassium, an aliphatic glucosinolate, is found in Brassica rapa vegetable crops [1].

Goitrin ((S)-Goitrin), formed through glucosinolate-myrosinase reactions, serves as a potent inhibitor of thyroid peroxidase, thereby hindering the thyroid's utilization of iodine. Additionally, it demonstrates anti-influenza virus (H1N1) activity.

Glucoraphenin potassium, the primary orally active glucosinolate found in radish sprouts, catalyzes the induction of xenobiotic metabolizing enzymes (XMEs). It is hydrolyzed by the enzyme myrosinase into sulforaphene, which is associated with anticancerogenic effects [1] [2].

Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moringin has anti-inflammatory and antioxidative properties.

Progoitrin is a thioglucoside that is predominantly associated with infected crops. It has an inhibitory effect on thyroid activity.

Sinigrin hydrate (Allylglucosinolate monohydrate) has antimicrobial activity. Sinigrin hydrate (Allylglucosinolate monohydrate) exerts important anti-proliferative activities in carcinogen-induced hepatocarcinogenesis in rats, and highlight the potential of Sinigrin as an anti-cancer agent for liver cancer.