gossypetin

Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3 6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects.It inhibits bone resorption by downregulating lysosomal caspase K activity and inducing autophagy-associated proteins in actin ring osteoclasts. Gossypetin has anti-mutagenic, anti-atherosclerotic, anti-oxidant, cytoprotective and antibacterial effects, and it inhibits bone resorption by down-regulating lysosomal caspase K activity and by inducing autophagy-associated protein in actin ring osteoblasts.

Gossypetin 3-sophoroside-8-glucoside, a flavonol glycoside, is extractable from the aerial parts of Equisetum hyemale L. [1].

Gossypetin 3′-O-glucoside, a gossypetin derivative, can be isolated from ethanolic extracts following Soxhlet extraction [1].

Gossypetin 3-methylether is a useful organic compound for research related to life sciences and the catalog number is T124054.