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gsk1482160

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  • Inhibitors & Agonists
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GSK1482160
T274501695551-19-9
GSK1482160 is a potent and selective P2X7 receptor allosteric modulator.
  • $1,520
6-8 weeks
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GSK-1482160
T610251001389-72-5
GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells, so GSK-1482160 has the potential to study inflammatory diseases. GSK-1482160 shows excellent in vitro potency (in functional and electrophysiological assays at recombinant and naive P2X7 receptors across multiple species including humans) and cross-target selectivity.
  • $48
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