gsk189254 hydrochloride

GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist.

GSK 3008348 hydrochloride is an integrin αvβ6 antagonist. The affinity (pIC50) for the human - a 6 protein in the Fluorescence Polarisation Assay for GSK 3008348 is 8.1, whereas its affinity in the cell Adhesion Assays was for ανβ6 (pIC50: 8.4); ανβ3 (pIC

GSK 189254A is a histamine H3 receptor antagonist for the treatment of narcolepsy. Histamine H3 receptor antagonists have been shown to increase the release of neurotransmitters in the brain and to enhance cognition in vivo. The compound may also be usefu

GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. is an ethyl ester derivative of the GSK-J1 with an IC50 value greater than 50 μM in vitro.

GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.

urotensin II (UT) receptor antagonist