h-3b-6527

Cbl-b-IN-3 is a potent inhibitor of casitas b lineage lymphoma proto-oncogene-b (Cbl-b) (ic50 < 1 nM).

h-NTPDase-IN-3 is an h-NTPDase inhibitor that inhibits h-NTPDase1, h-NTPDase2, h-NTPDase3 and h-NTPDase8.

H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) is an inhibitor of tyrosine hydroxylase (Ki = 0.39 M) and an intermediate in the synthesis of thyroid hormones

3-[7 ,7- dimethyl-5-oxo -6H-pyrrolo[3,4-b]pyridin-2-yI]-1H-indole-7 -carbonitrile is an androgen receptor modulator.

Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl) (3-methoxy-N-(3-(thiazolo[5,4-b]pyridin-2-yl)phenyl)benzamide) is a sirtuin modulator and useful for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including diabetes, cardiovascular disease, bloo

sodium 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate is an organosulfur compound. It has been used as a model compound to study the effects of sulfur-containing compounds on enzymatic activities and metabolic pathways. It has also been used to study the effects of sulfur-containing compounds on the regulation of bacterial growth and gene expression.

b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.

H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity.

(S)-2-Amino-3-(benzo[b]thiophen-3-yl)propanoic acid is an essential organic compound used in life sciences research. The catalog number is T66164 and the CAS number is 72120-71-9.

H-D-Phe(3-F)-OH, with catalog number T67306 and CAS number 110117-84-5, is a valuable organic compound for research in life sciences.

H-DL-Phe(3-Br)-OH is a useful organic compound for research related to life sciences. The catalog number is T66042 and the CAS number is 30163-20-3.

5-Acetyl-3-chloro-10,11-dihydro-5H-dibenz[b,f]azepine is a useful organic compound for research related to life sciences. The catalog number is T67591 and the CAS number is 25961-11-9.

H-3-D-Pal-OH.HCl, an amino acid derivative, has diverse applications in life science research.

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is a useful organic compound for research related to life sciences. The catalog number is T66536 and the CAS number is 256376-65-5.

3-Epimeliasenin B is a natural product for research related to life sciences. The catalog number is TN5953 and the CAS number is 1222475-77-5.

3-epi-Isocucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5972 and the CAS number is 89647-62-1.

Nucleoside Derivatives - 8-Aza-7-deaza purine nucleosides, Halo-nucleosides

DNA gyrase B-IN-3 (Compound A), with an IC50 of less than 10 nM, functions as an inhibitor of bacterial DNA gyrase B and demonstrates antibacterial activity against Gram-positive strains [1].

Nucleoside Derivatives –Fluoro-modified nucleosides, 6-Modified purine nucleosides, 3’-Modified nucleosides

Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.

hMAO-B-IN-3 (Compound 15) is a potent hMAO-B inhibitor (IC50 = 47.4 nM) with favorable drug-like properties and a broad safety window, making it a suitable candidate for lead optimization and multitarget-directed ligand development [1].

Quercetin 3-O-(6-O-malonyl)-b-D-glucoside is a useful organic compound for research related to life sciences. The catalog number is T123838 and the CAS number is 96862-01-0.

1-b-D-(3-Methoxy naphthalen-2-yl)-2’-deoxyriboside; 1,4-Anhydro-2-deoxy-1-C-(3-methoxy)-naphthalenyl)-D-erythro-pentitol is a useful organic compound for research related to life sciences. The catalog number is TNU1641 and the CAS number is 1117893-19-2.

Nucleoside Derivatives - 7-Deaza-8-aza purine nucleosides; Halo-nucleosides; 6-Modified purine nucleosides

H-(Gly)3-Lys(N3)-OH is a chemical reagent featuring an azide group prominently used in click chemistry for coupling with alkyne-containing fragments. Azides are extensively utilized for this purpose due to their effectiveness in such reactions. A polyglycine segment containing up to seven glycine residues has been reported to bind to surfaces, demonstrating potential applications in nanostructures; specifically, the Gly7-NHCH2 peptide segment binds to mica surfaces in aqueous solutions.

(2S,3S)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. This compound can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules that contain an alkyne group. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules featuring DBCO or BCN groups.

H-D-Phe(3-Br)-OH is a useful organic compound for research related to life sciences. The catalog number is T66311 and the CAS number is 99295-78-0.

(2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one is a useful organic compound for research related to life sciences. The catalog number is T65968 and the CAS number is 42399-49-5.

Benzo[b]thiophene-3-carbonitrile is a useful organic compound for research related to life sciences. The catalog number is T66350 and the CAS number is 24434-84-2.

4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1039.

3'-b-Amino-2',3'-dideoxy-5'-O-methoxytrityl-5-methyluridine is a Nucleoside Derivative - Amino-nucleoside, Xylo-nucleoside, 2',3'-Didexoy nucleoside, 3'-Modified nucleoside; Protected nucleoside with NH2/OH group.

Nucleoside Derivatives - Amino-nucleosides, Xylo-nucleosides, 2’,3’-Didexoy nucleosides, 3’-Modified nucleosides

AChE BChE MAO-B-IN-3, an indan-1-one derivative, is a potent inhibitor of human monoamine oxidase B (MAO-B) with an IC50 of 0.0359 μM and also demonstrates significant inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 0.0473 μM and 0.0782 μM, respectively. Exhibiting notable antioxidant activity, AChE BChE MAO-B-IN-3 holds considerable promise for Alzheimer's disease (AD) research.

4,5-Dihydroxy-2-((5-methyl-3,8-dimethylene-2-oxododecahydroazuleno[6,5-b]furan-5-yl)oxy)tetrahydro-2H-pyran-3-yl acetate is an α-arabinopyranosides analogue isolated from the aboveground parts of barley [1].

Anti-Mouse H-2K Antibody, an IgG2b isotype inhibitor targeting the mouse H-2K antigen, is sourced from a murine host.

(S)-3-((tert-Butoxycarbonyl)amino)-3-(3-(trifluoromethyl)phenyl)propanoic acid is a valuable organic compound for life sciences research, catalog number T66181 and CAS number 500770-78-5.

MAO-B-IN-3 is a selective, reversible inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and shows affinity for the 5-HT6 receptor with a Ki of 696 nM, making it suitable for Alzheimer's disease research [1].

(S)-9-((tert-Butyldimethylsilyl)oxy)-4,11-diethyl-4-hydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione is a useful organic compound for research related to life sciences and the catalog number is T64821.

(S)-tert-Butyl 2-(3-amino-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetate is a useful organic compound for research related to life sciences. The catalog number is T65674 and the CAS number is 109010-60-8.

3-Deoxysappanone B has vasorelaxation effects, it can mediate endothelium- independent vasodilator action in rat thoracic aortic rings.

6-Amino-3-ethynyl-4-methoxy-1-(b-D-ribofuranosyl)-1H- pyrazolo[3,4-d]pyrimidine is a Nucleoside Derivative - 8-Aza-7-deaza-purine nucleoside; 6-Modified purine nucleoside.

4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-2-O-acetyl-5-(O-p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1038.

Nucleoside Derivatives - 5-Modified pyrimidine nucleoside; 2’-Modified nucleoside; Protected nucleosides with NH2/OH open

Nucleoside Derivatives - 7-Deazapurine nucleosides; Halo-nucleosides; Scaffolds and Templates

6-Amino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one is a useful organic compound for research related to life sciences and the catalog number is TNU0282.

6-Amino-3-(furan-2-yl)-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a Nucleoside Derivative - 8-Aza-7-deaza-purine nucleoside; 6-Modified purine nucleoside.

H-(Gly)3-Lys(N3)-OH (hydrochloride) is a click chemistry reagent renowned for its high yield, specificity, and simplicity, making it an ideal choice for creating bindings among nucleic acids, lipids, proteins, and other molecules across various research domains.

H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide group. This compound enables copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that have an alkyne group. It can also undergo strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.