h8-a5

H8-A5, a HDAC8 inhibitor, shows antiproliferation activity in MDA-MB-231 cancer cells.

CCR1/5/8 activator 1 is a cytoplasmic phospholipase A inhibitor with antifungal activity.

5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may exhibit anti-influenza virus activity.

Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.

3,5,6,7,8,3',4'-Heptemthoxyflavone exhibits neuroprotective, chemopreventive, anti-allergic, anti-inflammatory, immunomodulatory, anti-aging, and photoprotective effects; it inhibits collagenase activity, induces type I procollagen synthesis in HDFn cells, and combats nitric oxide (NO) carcinogenesis.

3-Cyanovinyl-9-(5’-O-(4,4’-dimethoxytrityl)-2’-deoxyribofuranosyl)carbazole (trans: CAS#1044273-26-8) is a useful organic compound for research related to life sciences and the catalog number is TNU0955.

Mead acid, a 20-carbon ω-9 polyunsaturated fatty acid, experiences elevated levels in human plasma under conditions of essential fatty acid deficiency. As 1,25(Z),8(Z),11(Z)-Eicosatrienoic Acid methyl ester (Mead acid methyl ester), it frequently serves as a standard for fatty acid analysis, particularly after fatty acids have been transesterified into methyl esters.

Ethyl 8-hydroxy-alpha-(2-propynylamino)-5-quinolinepropanoate is a bioactive chemical.

[(2R,3S,4R,5R)-3,4-diacetyloxy-5-[2-amino-7-(cyclopropylmethyl)-8-oxopurin-9-yl]oxolan-2-yl]methyl acetate is a useful organic compound for research related to life sciences and the catalog number is TNU1306.

Phenanthridinium, 3-amino-8-(3-(3-(((aminoiminomethyl)hydrazono)methyl)phenyl)-1-triazenyl)-5-ethyl-6-phenyl-, chloride, monohydrochloride is a bioactive chemical.

5-Hydroxy-7-methoxy-8-methylflavanone is a useful organic compound for research related to life sciences and the catalog number is T131489.

5-Acetyl-8-(benzyloxy)quinolin-2(1H)-one is a useful organic compound for research related to life sciences. The catalog number is T66336 and the CAS number is 93609-84-8.

H-8 hydrochloride is a reversible and ATP-competitive PKA inhibitor. It can be used to study metabolic diseases.

(2R)-3α,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is derived exclusively from the roots of [Sophora flavescens].

3'-Deoxy-2',5'-di-O-acetyl-8-hydroxyguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside; 3'-Deoxy nucleoside.

5-Amino-8-hydroxyquinoline (5A8HQ) is a potential anticancer agent that has promising proteasome inhibitory activity.

H-Arg-Lys-OH TFA is a dipeptide formed from L-lysine residues and L-arginyl.

Phenanthridinium, 8-amino-6-(4-(3-(4-(aminoiminomethyl)phenyl)-1-triazenyl)phenyl)-5-methyl-, chloride, acetate is a bioactive chemical.

(6R,7R)-7-Amino-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66940 and the CAS number is 30246-33-4.

(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(tosyloxy)acetate is a useful organic compound for research related to life sciences and the catalog number is T64681.

5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450) and a metabolite of Xanthotoxin. It is used in the treatment of psoriasis, eczema, vitiligo, and certain cutaneous lymphomas in combination with phototherapy involving exposure to sunlight.

PROTAC(H-PGDS)-8 is a PROTAC degrader targeting Hematopoietic prostaglandin D synthase (H-PGDS), exhibiting an IC50 of 0.14 μM [1].

5’-modified nucleoside; halo-nucleoside

5-(Z-Heptadec-8-enyl)resorcinol is a natural product of Ardisia, Myrsinaceae. The catalog number is TN5637 and the CAS number is 52483-19-9. 5-(Z-Heptadec-8-enyl)resorcinol can be used as a reference standard.

7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine is a building block.1It has been used in the synthesis of PI3K inhibitors. 1.Scott, W.J., Hentemann, M.F., Rowley, R.B., et al.Discovery and SAR of novel 2,3-dihydroimidazo[1,2-c]quinazoline PI3K inhibitors: Identification of copanlisib (BAY 80-6946)ChemMedChem.11(14)1517-1530(2016)

Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66942 and the CAS number is 131666-45-0.

(R)-8-(Benzyloxy)-5-(2-bromo-1-hydroxyethyl)quinolin-2(1H)-one is a useful organic compound for research related to life sciences. The catalog number is T66255 and the CAS number is 530084-79-8.

Foxy-5 is a peptide that mimics the WNT5A protein and is expected to reduce the mobility of the cancer cells. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial c

8-Hydroxy-3,5,7,3',4',5'-hexamethoxyflavone, catalog number TN3279 and CAS number 202846-95-5, is a natural product used in life sciences research.

8-Chloroadenosine-5’-triphosphate (8-chloro ATP), a potent metabolite of the anticancer agent 8-chloro cyclic AMP (cAMP) and a nucleotide derivative, is produced through the biotransformation of 8-chloro cAMP into 8-chloroadenosine, followed by mono- and diphosphate intermediates. Accumulating for up to 12 hours after the administration of 8-chloro cAMP or 8-chloroadenosine, 8-chloro ATP inhibits cell growth, diminishes endogenous ATP levels, and reduces RNA synthesis without affecting DNA synthesis in multiple myeloma cells derived from patients. Moreover, it obstructs topoisomerase II-α-mediated relaxation of supercoiled pUC19 DNA at concentrations ranging from 1.5 to 8 mM and decreases topoisomerase II-α-enhanced ATP hydrolysis by 50% at a concentration of 1 mM in K562 human myelocytic leukemia cells.

(6R,7R)-4-Methoxybenzyl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65519 and the CAS number is 113479-65-5.

Phenanthridinium, 8-(acetylamino)-3-(3-(3-(aminoiminomethyl)phenyl)-1-triazenyl)-5-methyl-6-phenyl-, chloride, monohydrochloride is a bioactive chemical.

(R)-8-(Benzyloxy)-5-(2-((5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino)-1-hydroxyethyl)quinolin-2(1H)-one is a useful organic compound for research related to life sciences and the catalog number is T66254.

YKL-5-124 TFA is a potent, selective, irreversible and covalent inhibitor of CDK7 (IC50s of 53.5 nM and 9.7 nM for CDK7 and CDK7/Mat1/CycH, respectively).

2-Amino-8-hydroxypurine-9-beta-D-(2’,5’-di-O-acetyl-3’-deoxy)riboside is a useful organic compound for research related to life sciences. The catalog number is TNU1368 and the CAS number is 2389988-74-1.

(6R,7R)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T64947 and the CAS number is 24701-69-7.

2-(5-((3-Methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-ol is a useful organic compound for research related to life sciences and the catalog number is T64411.

(2'R,7R,8R,10S,13S,14S)-Methyl 10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,10,12,13,14,15,16-tetradecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T65404 and the CAS number is 95716-70-4.

Curcumin 5-8 (CUR5-8), a naturally active analog of curcumin (CUR), exhibits potent oral activity. It effectively inhibits lipid droplet formation, enhances autophagy, and reduces apoptosis. Additionally, Curcumin 5-8 has been shown to ameliorate insulin resistance and enhance insulin sensitivity [1].

8-Bromoguanosine-5'-O-triphosphate, a derivative of guanosine 5'-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition constant (Ki) of 31.8 µM. Furthermore, at a concentration of 500 µM, it facilitates the assembly of porcine brain microtubules in a cell-free assay.

N-(5-(8-Amino-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-2-methylphenyl)methanesulfonamide hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64837.

(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67310 and the CAS number is 79349-82-9.

2,6-Dibromo-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one is a useful organic compound for research related to life sciences. The catalog number is T64430 and the CAS number is 1415560-29-0.

(1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T67324 and the CAS number is 900160-98-7.

8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is a tetrasodium ATP analogue essential for energy storage and metabolic processes in living organisms. ATP, a key component in vivo, plays a critical role in these functions.

h-NTPDase-IN-5 (compound 3b) serves as a pan-inhibitor of NTPDase, exhibiting inhibitory concentration 50 (IC50) values of 1.10 μM [h-NTPDase1], 44.73 μM [h-NTPDase2], 26.14 μM [h-NTPDase3], and 0.32 μM [h-NTPDase8].

3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone is a natural product

8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen is a natural product of Psoralea (Fabaceae) with catalog number TN3281 and CAS number 425680-98-4, used as a reference standard.

8 beta-(4-Acetoxy-5-hydroxytigloyloxy)costunolide is a natural product for research related to life sciences. The catalog number is TN3302 and the CAS number is 109770-86-7.

Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II