hopegmal (mw 3400)

Biotin-PEG-Alk (MW 3400), a biotinylated polyethylene glycol (PEG) compound with an alkyne group, serves as a versatile click chemistry reagent. The biotin moiety acts as an enzyme cofactor desirable for protein labeling, PEG imparts hydrophilicity and aqueous solubility with minimal toxicity, and the alkyne (a type of acyclic hydrocarbon) facilitates efficient target binding by reacting with azides via copper-catalyzed azide-alkyne cycloaddition (CuAAC).

Biotin-PEG-azide (MW 3400) is a biotinylated polyethylene glycol (PEG) derivative featuring an azide group. Biotin serves as an enzyme co-factor suitable for protein labeling, while PEG is a hydrophilic, water-soluble, low-toxicity polymer. The azide group, a moderately good leaving group, undergoes Cu-catalyzed reactions with alkynes, enhancing the efficiency of target binding by biotin.

Biotin-PEG-OH (MW 3400) is a polymer comprised of biotin and polyethylene glycol (PEG) units [1].