hydratropamide, alpha-methyl-

Hydratropamide, alpha-methyl- is a bioactive chemical.

Methyl alpha-eleostearate (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1 cells supplemented with α-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 μM. It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 μM for different isoforms of the enzymes. α-ESA methyl ester is a neutral, more lipid soluble form of the free acid.

Benzyl alcohol, m-amino-alpha-methyl- is a bioactive chemical.

Benzyl alcohol, alpha-((4-amino-2-methoxyphenoxy)methyl)- is a bioactive chemical.

Phenethyl alcohol, m-chloro-alpha-((isopropylamino)methyl)-, hydrochloride is a bioactive chemical.

Cinnamic acid, m-chloro-alpha-methyl-, 7-nitro-8-quinolyl ester is a bioactive chemical.

m-Chloro-alpha-((dimethylamino)methyl)-beta-phenylphenetyl alcohol is a bioactive chemical.