hydroxy peg3 ch2 boc

Hydroxy-PEG3-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Hydroxy-PEG3-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative featuring a hydroxyl group and a Boc-protected amino group, used as a PROTAC linker.

Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker employed in PROTAC synthesis [1].

Hydroxy-PEG7-Boc, a PEG-based PROTAC linker, is utilized in PROTAC synthesis [1].

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

Hydroxy-PEG12-Boc (Hydroxy-PEG12-T-Butyl Ester) is a PEG-based PROTAC linker. Hydroxy-PEG12-Boc can be used in the synthesis of PROTACs.

Boc-NH-PEG3-CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis [1].

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Hydroxy-PEG6-Boc, a PEG-based PROTAC linker, is utilized in PROTAC synthesis [1].

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 is a synthetic E3 ligase ligand-linker conjugate composed of a VHL ligand and a linker, utilized in PROTAC BRD4 Degrader-5 and PROTAC BRD4 Degrader-5-CO-PEG3-N3.

2-Azido-PEG3-amido-13-biscarboxylethoxypropane is a polyethylene glycol (PEG)-based linker designed for constructing PROTACs.

Bromo-PEG3-CH2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Hydroxy-PEG3-SS-PEG3-alcohol, a 6-unit polyethylene glycol (PEG) linker that can be cleaved, is commonly used in the synthesis of antibody-drug conjugates (ADCs) [1].

N-(Azido-PEG3)-N-Boc-PEG4-Boc is a polyethylene glycol (PEG)-based proteolysis targeting chimeric (PROTAC) linker used in PROTAC synthesis[1].

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group, primarily used in PROTAC synthesis [1].

Aminooxy-PEG3-C2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Azido-PEG4-CH2-Boc, a four-unit cleavable polyethylene glycol (PEG) linker compound, is used in the synthesis of antibody-drug conjugates (ADCs) [1] and PROTACs [2]. Characterized by its azide functional group and PEG backbone, it facilitates drug-antibody conjugation in ADCs and enables PROTAC synthesis using PEG and alkyl ether moieties.

Hydroxy-PEG24-CH2-Boc is a PEG-based linker utilized in PROTACs, facilitating the connection of two essential ligands critical for PROTAC molecule formation, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Propargyl-PEG3-Boc, a PEG-based linker for PROTACs, connects two essential ligands vital for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Boc-Gly-amido-C-PEG3-C3-amine is a polyethylene glycol (PEG)-based PROTAC linker used in PROTAC synthesis [1].

Hydroxy-PEG20-Boc is a PEG-based linker for PROTACs, joining two essential ligands vital for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG3-C-Boc is a PEG-based linker for PROTACs that connects two essential ligands, crucial for the formation of PROTAC molecules, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Hydroxy-PEG3-acrylate is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

N-Boc-N-bis(PEG3-azide) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-(Boc-PEG2)-N-bis(PEG3-azide) is a polyethylene glycol (PEG)-derived linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Ald-CH2-PEG4-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Hydroxy-PEG4-CH2-Boc is a PEG-based linker used in PROTACs, facilitating the conjugation of two critical ligands necessary for PROTAC molecule formation. This linker enables selective protein degradation by exploiting the ubiquitin-proteasome system within cells.

N-Boc-N-bis(PEG3-NHS ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Tos-PEG6-CH2-Boc, a PEG-based linker for PROTACs, connects two essential ligands critical for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Hydroxy-Amino-bis(PEG1-C2-Boc) is an alkyl ether-based linker utilized in the synthesis of PROTACs [1].

NH-bis(PEG3-C2-NH-Boc) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-sulfonic acid, a polyethylene glycol (PEG) derived linker, is utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 serves as a linker for AUTAC4, a compound comprising a p-fluorobenzylguanine (FBnG) unit and a phenylindole moiety, capable of inducing K63-linked polyubiquitination and subsequent degradation of mitochondria within HeLa cells [1].

Hydroxy-PEG3-MS is a PEG-based linker for PROTACs [which joins two essential ligands], crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH), also known as (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH, is a conjugate compound comprising a ligand-linker that targets E3 ligase and features a VHL ligand on one end. It is employed in PROTAC technology applications.

A 410099.1 amide-PEG3-amine-Boc is an IAP ligand-based functionalized molecule commonly used in PROTACs, consisting of an IAP ligand and an amide-PEG3 linker with a terminal amine. The compound effectively conjugates with target protein ligands.

Methyl 1-Boc-azetidine-3-carboxylate, catalog number T66490 and CAS number 610791-05-4, is a valuable organic compound for life sciences research.

NH2-PEG2-CH2-Boc is a PEG-based linker for PROTACs, enabling the conjugation of two essential ligands for PROTAC molecule formation. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

1-N-Boc-3-hydroxyazetidine (catalog number: T67084, CAS number: 141699-55-0) is a valuable organic compound used in life sciences research.

m-PEG3-Boc is a PROTAC linker derived from PEG and alkyl ether, utilized in the synthesis of PROTACs[1].

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker and a cleavable 2-unit PEG ADC linker, used in the synthesis of PROTACs [1] and antibody-drug conjugates (ADCs) [2], respectively.

N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based linker compound used in the synthesis of PROTACs. [1]