hydroxy-peg4-c2-methyl ester

Hydroxy-PEG4-C2-methyl ester is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Br-C10-methyl ester, a PROTAC linker characterized by its alkyl ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a linker; notably, one ligand interacts with the VHL portion.

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

cis-4-Hydroxy-D-proline hydrochloride (catalog number T66933, CAS number 77449-94-6) is a valuable organic compound for research in life sciences.

D-Proline, 4-hydroxy-, methyl ester hydrochloride (T65606, CAS 114676-59-4) is a valuable organic compound for life sciences research.

m-PEG-Lys-NHS ester (MW 20,000) is an alkyl ether-based PROTAC linker commonly used in PROTAC synthesis[1].

N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a polyethylene glycol (PEG) derivative utilized as a PROTAC linker for synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Aminooxy-PEG3-methyl ester, a PEG-based PROTAC linker, serves as a pivotal element in the synthesis of PROTACs[1].

m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1].

Tos-PEG3-C2-methyl ester is a polyethylene glycol (PEG)-based linker used in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

trans-4-Hydroxy-D-proline hydrochloride, with catalog number T65471 and CAS number 142347-81-7, is a valuable organic compound for life sciences research.

Benzyl-PEG3-methyl ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

cis-4-Hydroxy-L-proline hydrochloride [catalog number: T65954, CAS number: 441067-49-8] is a valuable organic compound for life sciences research.

Azido-PEG1-methyl ester is an alkyl ether-based linker used in the synthesis of PROTACs (1).

Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine, a cleavable PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker, specifically Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane, widely used in the synthesis of PROTACs [1].

Hydroxy-PEG1-(CH2)2-Boc is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].

4-Methyl-4-(methyldisulfanyl)pentanoic acid is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and is designed to be cleavable.

Acid-PEG4-mono-methyl ester, a PEG- and Alkyl ether-based PROTAC linker, can be employed for PROTAC synthesis[1].

Propargyl-PEG3-methyl ester is a propargyl polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

N-Methyl-N'-(hydroxy-PEG2)-Cy5 is a PEG-based linker used in the synthesis of PROTACs, acting as a chemical compound that facilitates PROTAC formation [1].

DBCO-NHS ester 2 is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) and is a Dibenzylcyclooctyne (DBCO) derivative designed for copper-free click chemistry [1].

Hydroxy-PEG2-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).

Hydroxy-PEG3-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Hydroxy-PEG4-methyl acetate, a PEG-based linker compound, is utilized in PROTAC synthesis.

N-Boc-cis-4-hydroxy-D-proline methyl ester (catalog number: T66907, CAS number: 114676-69-6) is a valuable organic compound used in life sciences research.

N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a valuable organic compound for life sciences research. Its catalog number is T66976, and its CAS number is [147266-92-0].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-derived PROTAC linker used in the synthesis of PROTACs[1].

Hydroxy-PEG2-C2-PFP ester, a PEG Alkyl ether-based PROteolysis TArgeting Chimeric (PROTAC) linker, is suitable for the synthesis of PROTACs.

Hydroxy-PEG3-C2-methyl ester is a PEG-based PROTAC linker suitable for synthesizing PROTACs [1].

m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable one-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Hydroxy-PEG2-C2-methyl ester, a polyethylene glycol (PEG)-based linker, is commonly utilized for the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Methyl cis-4-Hydroxy-L-proline Hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65222 and the CAS number is 40126-30-5.

DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1]. DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1]. [1]. Mengzhu Zheng, et al. Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP. J Med Chem. 2021 May 26.

N-Boc-cis-4-hydroxy-L-proline is a valuable organic compound used in life sciences research (catalog number: T66248, CAS number: 87691-27-8).

Br-C3-methyl ester is an alkyl ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1 PD-L1 degrader-1.

Hydroxy-PEG3-PFP ester is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a polyethylene glycol (PEG)-based linker used for PROTAC synthesis [1].

Acid-PEG6-mono-methyl ester is a polyethylene glycol (PEG)-based PROTAC linker suitable for the synthesis of PROTACs [1].

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Hydroxy-PEG1-C2-methyl ester, a polyethylene glycol (PEG) derived linker, is widely used in the production of PROTACs (proteolysis targeting chimeras). [1]

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione-cleavable compound used for attaching monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs), specifically referring to the Alkyl-Chain composition of the linker portion of these molecules [1].

Bis-PEG-TFP ester (MW 5000) is a polyethylene glycol (PEG) based linker compound utilized in synthesizing Proteolysis Targeting Chimeras (PROTACs)[1].

Hydroxy-PEG5-C2-methyl ester, a polyethylene glycol (PEG) derived linker compound, is utilized in PROTAC (PROteolysis TArgeting Chimeras) synthesis[1].

Acid-PEG5-mono-methyl ester, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].