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i-ome-ag-538

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  • Inhibitors & Agonists
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I-OMe-Tyrphostin AG 538
I-OMe-AG 538
T115931094048-77-7In house
I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-deficient PANC1 cells.
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6-8 weeks
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Tyrphostin AG 538
AG 538
T67707133550-18-2In house
Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.
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8-10weeks
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