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Results for "
icapamespib hcl
" in TargetMol Product Catalog- Inhibitors & Agonists2
Icapamespib HCl
T697122267287-26-1
Icapamespib, also known as PU-HZ 151, is a heat shock protein 90 (HSP90) inhibitor. PU-HZ151 showed EC50 of 5 nM in the FP assay as compared to 11 nM for PU-H71 and a logD of 2.37 as compared to 1.21 for PU-H71. PU-HZ151 and radiolabeled PU-HZ151 showed selectivity for epichaperomes over the individual chaperome members. Icapamespib demonstrated the ability to productively engage the target in cells, mice, and humans.
- $1,520
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Icapamespib
T383911000999-96-1
Icapamespib (PU-HZ151), a potent HSP90 inhibitor, exhibits an EC50 of 5 nM and possesses the capability to cross the blood-brain barrier.
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