ihmt-pi3kδ-372 s-isomer

IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows high selectivity over other class I PI3Ks (56∼83 fold) and other protein kinases. IHMT-PI3Kδ-372 can be uesd for chronic obstructive pulmonary disease (COPD) research.

(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) is a chiral aromatic compound involved in phenylalanine metabolism. It is likely produced from phenylpyruvate via lactate dehydrogenase. The D-form is derived from bacterial sources, while the L-form is endogenous. Phenyllactate levels are normally very low in blood or urine, but high levels indicate phenylketonuria (PKU) and hyperphenylalaninemia (HPA). PKU is due to a deficiency of phenylalanine hydroxylase (PAH), causing phenylalanine to convert to phenylpyruvic acid rather than tyrosine.

(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver from acetyl-CoA in humans, and can be used as an energy source by the brain when blood glucose is low.

(S)-OSMI 3 (Ent-OSMI-3) has anti-inflammatory and anti-tumour activity and can be used to study diabetes and neurodegenerative diseases.

(S)-6-methoxychroman-3-carboxylic acid is a synthetic compound with a molecular formula of C11H10O5. It is a member of the chroman family of compounds, which are characterized by a seven-membered ring with one oxygen and one carbon atom.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).

(S)-2-((R)-3-(4-chlorophenyl)-N’-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-methylbutanamide is a cannabinoid receptor antagonist/inverse agonist.

(S)-3-AMino-2-Methylpropanoic acid-HCl is an amino acid derivative that can be an agonist of the excitatory neurotransmitter glutamate and affect the nervous system.

Compound Fr12310 is a useful organic compound for research related to life sciences. The catalog number is Fr12310 and the CAS number is 101385-90-4.

(S)-3-(4-Hydroxyphenyl)-2-hydroxypropionic acid ((S)-3-(4-Hydroxyphenyl)lactic acid) (compound 1) is a metabolite found in the culture medium of Leuconostoc mesenteroides, exhibiting significant DPPH radical-scavenging and antioxidative activities.

(S)-3-Thienylglycine is a thiophene derivative and can be used to investigate the genotoxicity of the similar structures with thiophene derivatives.

IHMT-PI3Kδ-372 is a selective inhibitor of PI3Kδ with an IC50 of 14 nM and can be used in studies about chronic obstructive pulmonary disease.

(S)-2-Amino-3-(thiophen-2-yl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T67042 and the CAS number is 22951-96-8.

(S)-3-Amino-2-hydroxypropanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66008 and the CAS number is 632-13-3.

(S)-3-Amino-1-chloro-5-methylhexan-2-one hydrochloride [catalog number T65276, CAS number 54518-92-2] is a valuable organic compound for life sciences research.

(S)-Methyl 2-amino-3-cyclohexylpropanoate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66551 and the CAS number is 17193-39-4.

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-(tosyloxy)propanoate is a useful organic compound for research related to life sciences. The catalog number is T66053 and the CAS number is 56926-94-4.

(S)-3-Aminohexanedioic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66088 and the CAS number is 61884-74-0.

(S)-2-((tert-Butoxycarbonyl)amino)-3-(thiophen-2-yl)propanoic acid [T65340, CAS 56675-37-7] is a valuable organic compound for life sciences research.

(S)-2-Amino-3-(benzo[b]thiophen-3-yl)propanoic acid is an essential organic compound used in life sciences research. The catalog number is T66164 and the CAS number is 72120-71-9.

(S)-2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65545 and the CAS number is 1676-75-1.

(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-3-methylbutanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65969 and the CAS number is 42417-65-2.

AZD6482 (S-isomer) is a potent, selective, ATP-competitive PI3Kβ inhibitor (IC(50) 0.01 μm), which can inhibit insulin-induced in vitro glucose uptake by human adipocytes (IC(50) is 4.4 μm).

'(S)-ICMT-IN-3 (compound ent 1-27) is an ICMT inhibitor with an IC50 value of 0.23 μM [1].'

(S)-3-(Allyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid is a useful organic compound for research related to life sciences and the catalog number is T64551.

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 μM.

group I metabotropic glutamate receptor antagonist and group II mGlu agonist

(S)-2-((tert-Butoxycarbonyl)amino)-3-(2-methoxyphenyl)propanoic acid is a useful organic compound for research related to life sciences and the catalog number is T67248.

(S)-(-)-3-(N-Methylamino)-1-(2-thienyl)-1-propanol is a useful organic compound for research related to life sciences. The catalog number is T67011 and the CAS number is 116539-55-0.

1-O-Caffeoyl-3-O-galloyl-4,6-(S)-hexahydroxydiphen is a useful organic compound for research related to life sciences. The catalog number is T124953 and the CAS number is 359828-21-0.

(S)-4-(Amino(carboxy)methyl)-3-methylbenzoic acid hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64800.

(S)-2-(2,6-Dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione is a useful organic compound for research related to life sciences and the catalog number is T64820.

(S)-(+)-3-Hydroxytetrahydrofuran is a useful organic compound for research related to life sciences. The catalog number is T66897 and the CAS number is 86087-23-2.

(S)-3-(1-(Dimethylamino)ethyl)phenol is a useful organic compound for research related to life sciences. The catalog number is T65737 and the CAS number is 139306-10-8.

S-(3-Carboxypropyl)-L-cysteine is a thioether derivative of L-cysteine.

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid with stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position, produced by oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-lipoxygenase (15-LO). At concentrations of 0.6 and 0.9 μM, it increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.

6-S-(2-Cyanoethyl)-2’-deoxy-5’-O-DMTr-6-thioguanosine 3’-CED phosphoramidite [catalog number TNU1665] is an essential organic compound for life sciences research.

(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channels, activating Ba2+ currents with an EC50 of 32 nM.

(S)-1-(4-Fluorophenyl)-5-(2-oxo-4-phenyloxazolidin-3-yl)pentane-1,5-dione is a useful organic compound for research related to life sciences. The catalog number is T65826 and the CAS number is 189028-93-1.

(2S,2'S)-1,1'-(2,2'-((3-Hydroxyadamantan-1-yl)azanediyl)bis(acetyl))bis(pyrrolidine-2-carbonitrile) is a useful organic compound for research related to life sciences and the catalog number is T64479.

(S)-Methyl 2-amino-3-(3-hydroxyphenyl)propanoate hydrochloride, with catalog number T66437 and CAS number 34260-72-5, is a valuable organic compound for life science research.

(S)-2-Amino-3-hydroxypropanamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66126 and the CAS number is 65414-74-6.

(S)-2-Amino-3-(naphthalen-1-yl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T65385 and the CAS number is 55516-54-6.

(S)-2-(2-Amino-3-phenylpropanamido)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T65244 and the CAS number is 721-90-4.

(S)-2-Amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T66863 and the CAS number is 38739-13-8.

(S)-Methyl 3-amino-2-((tert-butoxycarbonyl)amino)propanoate hydrochloride is a valuable organic compound for life sciences research [Catalog Number: T66364, CAS Number: 181228-33-1].

(S)-2-((tert-Butoxycarbonyl)amino)-3-cyclohexylpropanoic acid is a valuable organic compound for life sciences research [Catalog No. T65497, CAS No. 37736-82-6].