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  • Apoptosis
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  • JAK
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  • Mitophagy
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  • Tyrosine Kinases
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incb 018424

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    3
    TargetMol | Activity
Ruxolitinib phosphate
T30431092939-17-7
Ruxolitinib phosphate (INCB018424)(INCB018424 phosphate) is the first potent, selective, JAK1 2 inhibitor to enter the clinic with IC50 of 3.3 nM 2.8 nM, >130-fold selectivity for JAK1 2 versus JAK3.
  • $44
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Ruxolitinib
T1829941678-49-5
Ruxolitinib (INCB018424) is a JAK1 2 inhibitor (IC50=3.3 2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
  • $53
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TargetMol | Citations Cited
Ruxolitinib (S enantiomer)
T6156941685-37-6
Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.
  • $58
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