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(1)
By Target- Apoptosis
- Autophagy(2)
- JAK(3)
- Mitophagy(2)
- Tyrosine Kinases(2)
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Biochemicals
- Autophagy
- Cell Cycle/Checkpoint
- Cytoskeletal Signaling
- Chromatin/Epigenetic
- Endocrinology/Hormones
- Hedgehog/Smoothened
- Angiogenesis
- DNA Damage/DNA Repair
- Apoptosis
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Results for "
incb-018424
" in TargetMol Product Catalog- Inhibitors & Agonists3
Ruxolitinib
Cited
INCB018424,(R)-Ruxolitinib
T1829941678-49-5
Ruxolitinib (INCB018424) is a JAK1 2 inhibitor (IC50=3.3 2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
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CitedRuxolitinib phosphate Cited
INC424,INCB018424,INC 424 phosphate,Ruxolitinib (INCB-18424) phosphate,INCB018424 phosphate
T30431092939-17-7
Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1 2 inhibitor with IC50 of 3.3 nM 2.8 nM. Its selectivity for JAK1 2 is more than 130 times that of JAK3.
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CitedRuxolitinib (S enantiomer)
S-Ruxolitinib,Ruxolitinib S enantiomer,INCB018424,INCB18424
T6156941685-37-6
Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.
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