influenza np (147155)

CEF8, Influenza Virus NP (383-391) is an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated with escape from cytotoxic T lymphocytes-mediated immunity.HLA-B*3501 restricted influenza virus nucleoprotein epitope (383-391).

Influenza NP (311-325) is a biologically active peptide composed of amino acids 311 to 325 derived from the influenza virus nucleoprotein (NP). As a bona fide MHC class II-restricted epitope, it is instrumental for studying host immune responses during viral infection. It notably induces robust gamma interferon (IFN-gamma) production in intracellular cytokine assays while not stimulating CD8 T-cells in mice. Additionally, the presence of Glutamine (Q) or Glutamic acid (E) at the N-terminus can lead to the spontaneous formation of Pyroglutamyl (pGlu) peptides, which may enhance peptide stability against gastrointestinal proteases through the hydrophobic γ-lactam ring of pGlu. Consequently, these peptides are considered a normal variant and factored into the peptide purity measurements in HPLC analysis.

This peptide is a H-2Kd-restricted epitope from Influenza nucleoprotein (147-155).

This peptide is a H2-Db-restricted epitope from Influenza nucleoprotein (147-155).

This peptide is an H2-Db-restricted epitope from the Influenza A/PR/8/34 nucleoprotein.

HLA-B*08 restricted influenza virus nucleoprotein epitope.